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PN-477 (Oral)

Obesity & Co-morbidities

IND-EnablingPhase 1 initiation 2H '26

Key Facts

Indication
Obesity & Co-morbidities
Phase
IND-Enabling
Status
Phase 1 initiation 2H '26
Company

About Protagonist Therapeutics

Protagonist Therapeutics is a leader in peptide-based drug discovery, leveraging its proprietary Vectrix™ platform to overcome historical challenges of oral bioavailability and stability. The company has achieved significant milestones, including the FDA approval of icotrokinra for psoriasis and a pending NDA for rusfertide in polycythemia vera. Its strategy combines internal development of wholly-owned assets with strategic partnerships, like the one with Janssen for icotrokinra, to build a diversified, multi-indication portfolio.

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Other Obesity & Co-morbidities Drugs

DrugCompanyPhase
PN-477 (SC)Protagonist TherapeuticsIND-Enabling