Pelareorep
Second-line KRAS-mutant MSS Metastatic Colorectal Cancer (mCRC)
Key Facts
About Oncolytics Biotech
Oncolytics Biotech is singularly focused on developing its first-in-class, intravenously delivered oncolytic reovirus, pelareorep, as a platform immunotherapy for gastrointestinal (GI) tumors. The company has generated compelling clinical data across multiple GI cancers, including metastatic pancreatic ductal adenocarcinoma (mPDAC), KRAS-mutant metastatic colorectal cancer (mCRC), and squamous cell carcinoma of the anus (SCAC), demonstrating survival benefits that significantly exceed historical benchmarks. Its strategy is to advance these programs into registration-focused studies, leveraging Fast Track Designation in pancreatic and colorectal cancer to potentially accelerate the path to market.
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