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Motixafortide

Stem cell mobilization for gene therapy in sickle cell disease

Phase 1/2Active (Investigator Initiated Studies NCT06442761, NCT05618301)

Key Facts

Indication
Stem cell mobilization for gene therapy in sickle cell disease
Phase
Phase 1/2
Status
Active (Investigator Initiated Studies NCT06442761, NCT05618301)
Companies

About Gamida Cell

Gamida Cell pioneers nicotinamide-enhanced allogeneic cell therapies for hematologic conditions, with two FDA-approved products for transplantation and stem cell mobilization.

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About BioLineRx

BioLineRx is a publicly traded, Israeli biotech company with a mission to develop best-in-class therapies for oncology and rare diseases. Its core strategy involves in-licensing and advancing novel drug candidates through clinical proof-of-concept, exemplified by the successful FDA approval and out-licensing of its stem cell mobilizer, motixafortide (APHEXDA®). The company has now pivoted back to a lean development model, focusing its resources on a promising new joint venture for GLIX1 in glioblastoma and a partnered Phase 2b trial in pancreatic cancer.

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About BioLineRx

BioLineRx is a publicly traded, Israeli biotech company with a mission to develop best-in-class therapies for oncology and rare diseases. Its core strategy involves in-licensing and advancing novel drug candidates through clinical proof-of-concept, exemplified by the successful FDA approval and out-licensing of its stem cell mobilizer, motixafortide (APHEXDA®). The company has now pivoted back to a lean development model, focusing its resources on a promising new joint venture for GLIX1 in glioblastoma and a partnered Phase 2b trial in pancreatic cancer.

View full company profile

About BioLineRx

BioLineRx is a publicly traded, Israeli biotech company with a mission to develop best-in-class therapies for oncology and rare diseases. Its core strategy involves in-licensing and advancing novel drug candidates through clinical proof-of-concept, exemplified by the successful FDA approval and out-licensing of its stem cell mobilizer, motixafortide (APHEXDA®). The company has now pivoted back to a lean development model, focusing its resources on a promising new joint venture for GLIX1 in glioblastoma and a partnered Phase 2b trial in pancreatic cancer.

View full company profile