Lymphotoxin-alpha-based therapy
Acute Myeloid Leukemia (AML)
Key Facts
About Cycuria Therapeutics
Cycuria Therapeutics is a private, preclinical-stage biotech based in Graz, Austria, developing engineered biologic therapies for hard-to-treat cancers, with an initial focus on acute myeloid leukemia (AML). The company's proprietary platform aims to create first-in-class therapies that specifically eradicate leukemic stem cells, a key driver of relapse, while minimizing toxicity to healthy hematopoiesis. Led by a team with expertise in protein engineering and hemato-oncology, Cycuria is advancing a novel approach based on lymphotoxin-alpha biology, as evidenced by recent promising preclinical publications. The company is positioned to address a large market with high unmet need, particularly in older AML patients who cannot tolerate intensive standard therapies.
View full company profileTherapeutic Areas
Other Acute Myeloid Leukemia (AML) Drugs
| Drug | Company | Phase |
|---|---|---|
| Mipletamig (APVO436) | Aptevo Therapeutics | Phase 1/2 |
| lomonitinib | Lomond Therapeutics | IND-Enabling |
| lonitoclax | Lomond Therapeutics | Phase 1 |
| Menin Inhibitor | Lomond Therapeutics | Discovery |
| AB8939 | AB Science | Phase 1 |
| Small-Molecule Therapeutic | AIkido Labs | Pre-clinical |
| ADI-PEG 20 (pegargiminase) | Polaris Pharma | Phase 1 |
| NC525 | NextCure | Preclinical |
| ACD-101 | Advanced Cellular Dynamics | Phase 1 |
| ABD-3001 | Advanced Biodesign | Phase 1 |
| HC-7366 | HiberCell | Phase 1b |
| Prexigebersen (BP1001) | Bio-Path Holdings | Phase 2 |