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ABD-3001

Acute Myeloid Leukemia (AML)

Phase 1Active (trial began early 2023)

Key Facts

Indication
Acute Myeloid Leukemia (AML)
Phase
Phase 1
Status
Active (trial began early 2023)
Company

About Advanced Biodesign

Advanced BioDesign is a French biotech founded in 2010 with a mission to treat chemotherapy-resistant cancers by targeting the ALDH1 enzyme family, a key driver of tumor drug resistance and immunomodulation. The company has progressed its lead small-molecule inhibitor, ABD-3001, into clinical trials for AML and has a promising pre-clinical pipeline for solid tumors. Its integrated strategy combines therapeutic inhibitors with a companion diagnostic, ALDESCREEN®, aiming to personalize treatment and improve outcomes for patients with resistant cancers.

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About Advanced Biodesign

Advanced BioDesign is a French biotech founded in 2010 with a mission to treat chemotherapy-resistant cancers by targeting the ALDH1 enzyme family, a key driver of tumor drug resistance and immunomodulation. The company has progressed its lead small-molecule inhibitor, ABD-3001, into clinical trials for AML and has a promising pre-clinical pipeline for solid tumors. Its integrated strategy combines therapeutic inhibitors with a companion diagnostic, ALDESCREEN®, aiming to personalize treatment and improve outcomes for patients with resistant cancers.

View full company profile

About Advanced Biodesign

Advanced BioDesign is a French biotech founded in 2010 with a mission to treat chemotherapy-resistant cancers by targeting the ALDH1 enzyme family, a key driver of tumor drug resistance and immunomodulation. The company has progressed its lead small-molecule inhibitor, ABD-3001, into clinical trials for AML and has a promising pre-clinical pipeline for solid tumors. Its integrated strategy combines therapeutic inhibitors with a companion diagnostic, ALDESCREEN®, aiming to personalize treatment and improve outcomes for patients with resistant cancers.

View full company profile

About Advanced Biodesign

Advanced BioDesign is a French biotech founded in 2010 with a mission to treat chemotherapy-resistant cancers by targeting the ALDH1 enzyme family, a key driver of tumor drug resistance and immunomodulation. The company has progressed its lead small-molecule inhibitor, ABD-3001, into clinical trials for AML and has a promising pre-clinical pipeline for solid tumors. Its integrated strategy combines therapeutic inhibitors with a companion diagnostic, ALDESCREEN®, aiming to personalize treatment and improve outcomes for patients with resistant cancers.

View full company profile

Therapeutic Areas

Other Acute Myeloid Leukemia (AML) Drugs

DrugCompanyPhase
Mipletamig (APVO436)Aptevo TherapeuticsPhase 1/2
lomonitinibLomond TherapeuticsIND-Enabling
lonitoclaxLomond TherapeuticsPhase 1
Menin InhibitorLomond TherapeuticsDiscovery
AB8939AB SciencePhase 1
Small-Molecule TherapeuticAIkido LabsPre-clinical
ADI-PEG 20 (pegargiminase)Polaris PharmaPhase 1
NC525NextCurePreclinical
ACD-101Advanced Cellular DynamicsPhase 1
HC-7366HiberCellPhase 1b
Prexigebersen (BP1001)Bio-Path HoldingsPhase 2
oNKord® (Inaleucel)GlycostemPhase 1/2a