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ABD-3001

Acute Myeloid Leukemia (AML)

Phase 1Active (trial began early 2023)

Key Facts

Indication
Acute Myeloid Leukemia (AML)
Phase
Phase 1
Status
Active (trial began early 2023)
Company

About Advanced Biodesign

Advanced BioDesign is a French biotech founded in 2010 with a mission to treat chemotherapy-resistant cancers by targeting the ALDH1 enzyme family, a key driver of tumor drug resistance and immunomodulation. The company has progressed its lead small-molecule inhibitor, ABD-3001, into clinical trials for AML and has a promising pre-clinical pipeline for solid tumors. Its integrated strategy combines therapeutic inhibitors with a companion diagnostic, ALDESCREEN®, aiming to personalize treatment and improve outcomes for patients with resistant cancers.

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About Advanced Biodesign

Advanced BioDesign is a French biotech founded in 2010 with a mission to treat chemotherapy-resistant cancers by targeting the ALDH1 enzyme family, a key driver of tumor drug resistance and immunomodulation. The company has progressed its lead small-molecule inhibitor, ABD-3001, into clinical trials for AML and has a promising pre-clinical pipeline for solid tumors. Its integrated strategy combines therapeutic inhibitors with a companion diagnostic, ALDESCREEN®, aiming to personalize treatment and improve outcomes for patients with resistant cancers.

View full company profile

About Advanced Biodesign

Advanced BioDesign is a French biotech founded in 2010 with a mission to treat chemotherapy-resistant cancers by targeting the ALDH1 enzyme family, a key driver of tumor drug resistance and immunomodulation. The company has progressed its lead small-molecule inhibitor, ABD-3001, into clinical trials for AML and has a promising pre-clinical pipeline for solid tumors. Its integrated strategy combines therapeutic inhibitors with a companion diagnostic, ALDESCREEN®, aiming to personalize treatment and improve outcomes for patients with resistant cancers.

View full company profile

About Advanced Biodesign

Advanced BioDesign is a French biotech founded in 2010 with a mission to treat chemotherapy-resistant cancers by targeting the ALDH1 enzyme family, a key driver of tumor drug resistance and immunomodulation. The company has progressed its lead small-molecule inhibitor, ABD-3001, into clinical trials for AML and has a promising pre-clinical pipeline for solid tumors. Its integrated strategy combines therapeutic inhibitors with a companion diagnostic, ALDESCREEN®, aiming to personalize treatment and improve outcomes for patients with resistant cancers.

View full company profile

Therapeutic Areas

Other Acute Myeloid Leukemia (AML) Drugs

DrugCompanyPhase
NTLA-5001Intellia TherapeuticsPhase 1/2
Galinpepimut-S (GPS)SELLAS Life SciencesPhase 2/3
SLS009 (GFH009)SELLAS Life SciencesPhase 1/2
UCART123CellectisPhase 1
Iadademstat (ORY-1001)Oryzon GenomicsPhase 2
MP0533Molecular PartnersPhase 1/2
SEL24 (MEN1703)SelvitaPhase 1/2
SelinexorKaryopharm TherapeuticsClinical Trials
NEX-20 (azacitidine)Nanexa ABPhase 1
SENTI-202Senti BiosciencesPhase 1
motixafortide (BL-8040)BioLineRxPhase 2a
ACD-101Advanced Cellular DynamicsPhase 1