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Efzofitimod (ATYR1923)

Pulmonary Sarcoidosis

Phase 3Topline results announced Sept 2025NCT05864391

Key Facts

Indication
Pulmonary Sarcoidosis
Phase
Phase 3
Status
Topline results announced Sept 2025
Company

About aTyr Pharma

aTyr Pharma is translating the groundbreaking discovery of extracellular tRNA synthetase biology into a new class of protein-based therapeutics for fibrosis and inflammation. Its lead asset, efzofitimod, has reported Phase 3 topline results in pulmonary sarcoidosis and is in a Phase 2 study for SSc-ILD, targeting diseases with high unmet need. The company's strategy is to advance its proprietary platform to generate a pipeline of immunomodulators while exploring bispecific antibody opportunities through its Pangu BioPharma subsidiary.

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About aTyr Pharma

aTyr Pharma is translating the groundbreaking discovery of extracellular tRNA synthetase biology into a new class of protein-based therapeutics for fibrosis and inflammation. Its lead asset, efzofitimod, has reported Phase 3 topline results in pulmonary sarcoidosis and is in a Phase 2 study for SSc-ILD, targeting diseases with high unmet need. The company's strategy is to advance its proprietary platform to generate a pipeline of immunomodulators while exploring bispecific antibody opportunities through its Pangu BioPharma subsidiary.

View full company profile

Other Pulmonary Sarcoidosis Drugs

DrugCompanyPhase
SM001 (alidornase/Tigerase)SarcoMed USAPre-clinical
XTMAB-16XentriaPhase 2