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eDSP (EryDex)

Ataxia-Telangiectasia (A-T)

Phase 3Pivotal NEAT trial completed Jan 2026; primary endpoint not met. Under strategic review.

Key Facts

Indication
Ataxia-Telangiectasia (A-T)
Phase
Phase 3
Status
Pivotal NEAT trial completed Jan 2026; primary endpoint not met. Under strategic review.
Company

About Quince Therapeutics

Quince Therapeutics is a clinical-stage biotech focused on transforming proven therapeutics through its innovative Autologous Intracellular Drug Encapsulation (AIDE) platform, which leverages a patient's own red blood cells for targeted, safer drug delivery. The company's most advanced candidate, eDSP, recently reported topline results from a pivotal Phase 3 trial in Ataxia-Telangiectasia (A-T), which did not meet its primary or key secondary endpoints, prompting a strategic review. Quince's strategy hinges on leveraging the AIDE platform's potential to improve the therapeutic index of corticosteroids and other drugs across multiple chronic inflammatory and rare diseases, though its near-term future is contingent on the outcome of its exploration of strategic alternatives.

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