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EB612 (oral PTH(1-34))

Hypoparathyroidism

Phase 2Active; Partnership with OPKO

Key Facts

Indication
Hypoparathyroidism
Phase
Phase 2
Status
Active; Partnership with OPKO
Company

About Entera Bio

Entera Bio is a clinical-stage biotech focused on transforming injectable peptide therapies into convenient oral tablets using its proprietary N-Tab® drug delivery platform. The company's strategy de-risks development by targeting well-characterized peptides like PTH, with its lead asset, EB613 for osteoporosis, having completed a positive Phase 2 study and a streamlined Phase 3 protocol submitted in early 2026. Backed by a seasoned management team and strategic partnerships, Entera aims to redefine standards of care by improving patient adherence and enabling earlier therapeutic intervention.

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Other Hypoparathyroidism Drugs

DrugCompanyPhase
EB-612Extend BiosciencesPhase 2
Hypoparathyroidism ProgramConfo TherapeuticsDiscovery
Oral Long-Acting PTH TabletOpko HealthPre-clinical/Phase 1
Canvuparatide (MBX 2109)MBX BiosciencesPhase 2
SEP-479 (PTH1R)SepternaPhase 2
Oral Long-Acting PTHEntera BioDiscovery/Preclinical