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CASGEVY™ (exagamglogene autotemcel)

Transfusion-Dependent Beta Thalassemia

ApprovedCommercial

Key Facts

Indication
Transfusion-Dependent Beta Thalassemia
Phase
Approved
Status
Commercial
Company

About CRISPR Therapeutics

CRISPR Therapeutics' mission is to develop curative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. Its landmark achievement is the approval of CASGEVY™ (exa-cel), the world's first CRISPR-based therapy, developed with Vertex Pharmaceuticals for sickle cell disease and beta thalassemia. The company's strategy leverages a fully integrated R&D and manufacturing infrastructure to advance a diversified clinical pipeline, including allogeneic CAR-T therapies for oncology and programs in regenerative medicine. CRISPR Therapeutics aims to sustain its first-mover advantage by expanding the applications of gene editing across multiple therapeutic areas.

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About CRISPR Therapeutics

CRISPR Therapeutics' mission is to develop curative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. Its landmark achievement is the approval of CASGEVY™ (exa-cel), the world's first CRISPR-based therapy, developed with Vertex Pharmaceuticals for sickle cell disease and beta thalassemia. The company's strategy leverages a fully integrated R&D and manufacturing infrastructure to advance a diversified clinical pipeline, including allogeneic CAR-T therapies for oncology and programs in regenerative medicine. CRISPR Therapeutics aims to sustain its first-mover advantage by expanding the applications of gene editing across multiple therapeutic areas.

View full company profile

Other Transfusion-Dependent Beta Thalassemia Drugs

DrugCompanyPhase
Exagamglogene Autotemcel (CASGEVY)Vertex PharmaceuticalsApproved