CRISPR Therapeutics

CRISPR Therapeutics

CRSP
Zug, Switzerland· Est.
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CRSP · Stock Price

USD 52.42+16.80 (+47.16%)
Market Cap: $5.1B

Historical price data

Market Cap: $5.1BPipeline: 8 drugsPatents: 20Founded: 2013Employees: 500-1000HQ: Zug, Switzerland

Overview

CRISPR Therapeutics' mission is to develop curative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. Its landmark achievement is the approval of CASGEVY™ (exa-cel), the world's first CRISPR-based therapy, developed with Vertex Pharmaceuticals for sickle cell disease and beta thalassemia. The company's strategy leverages a fully integrated R&D and manufacturing infrastructure to advance a diversified clinical pipeline, including allogeneic CAR-T therapies for oncology and programs in regenerative medicine. CRISPR Therapeutics aims to sustain its first-mover advantage by expanding the applications of gene editing across multiple therapeutic areas.

HemoglobinopathiesOncologyRegenerative MedicineAutoimmune DiseasesCardiovascular Disease

Technology Platform

A proprietary CRISPR/Cas9 gene-editing platform enabling precise DNA modifications, utilized for both ex vivo cell engineering (e.g., edited stem cells, allogeneic CAR-Ts) and the development of in vivo delivery systems to treat diseases directly inside the body.

Pipeline

8
8 drugs in pipeline
DrugIndicationStageWatch
CTX112B-cell LymphomaPhase 1/2
CTX110B-cell MalignancyPhase 1/2
CTX131Clear Cell Renal Cell CarcinomaPhase 1/2
CTX131T Cell LymphomaPhase 1/2
CTX120Multiple MyelomaPhase 1

Funding History

4
Total raised:$421M
PIPE$200M
IPO$56M
Series B$140M
Series A$25M

Company Timeline

2013Founded

Founded in Zug, Switzerland

2015Series B

Series B: $140.0M

2016IPO

IPO — $56.0M

2020PIPE

PIPE: $200.0M