CRISPR Therapeutics
CRSPPhase 2CRISPR Therapeutics is a pioneering biopharmaceutical company dedicated to discovering, developing, and commercializing curative gene-editing treatments. Founded by CRISPR gene-editing pioneers, the company leverages its proprietary CRISPR/Cas9 platform to create a diverse pipeline targeting hemoglobinopathies, immuno-oncology, regenerative medicine, and in vivo diseases. Its landmark achievement is the approval of CASGEVY, the world's first CRISPR/Cas9 gene-edited therapy, marking a new era in medicine and validating its platform's potential. The company collaborates with Vertex Pharmaceuticals and Bayer to accelerate development and commercialization across multiple therapeutic areas.
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AI Company Overview
CRISPR Therapeutics is a pioneering biopharmaceutical company dedicated to discovering, developing, and commercializing curative gene-editing treatments. Founded by CRISPR gene-editing pioneers, the company leverages its proprietary CRISPR/Cas9 platform to create a diverse pipeline targeting hemoglobinopathies, immuno-oncology, regenerative medicine, and in vivo diseases. Its landmark achievement is the approval of CASGEVY, the world's first CRISPR/Cas9 gene-edited therapy, marking a new era in medicine and validating its platform's potential. The company collaborates with Vertex Pharmaceuticals and Bayer to accelerate development and commercialization across multiple therapeutic areas.
Technology Platform
Proprietary CRISPR/Cas9 gene-editing platform enabling both ex vivo (cell therapy) and in vivo (direct administration) therapeutic approaches, with a focus on allogeneic (off-the-shelf) cell therapies.
Pipeline Snapshot
88 drugs in pipeline
| Drug | Indication | Stage | Watch |
|---|---|---|---|
| CTX112 | B-cell Lymphoma | Phase 1/2 | |
| CTX110 | B-cell Malignancy | Phase 1/2 | |
| CTX131 | Clear Cell Renal Cell Carcinoma | Phase 1/2 | |
| CTX131 | T Cell Lymphoma | Phase 1/2 | |
| CTX130 | Renal Cell Carcinoma | Phase 1 |
Funding History
4Total raised: $421M
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Competitive Landscape
Main competitors include bluebird bio in hemoglobinopathies, and Allogene Therapeutics, Caribou Biosciences, and Intellia Therapeutics in the broader gene-editing and allogeneic cell therapy space. CRISPR Therapeutics differentiates through its first-mover approval, integrated platform spanning ex vivo and in vivo approaches, and strong strategic partnerships.
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