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Atacicept

IgA Nephropathy (IgAN)

Phase 2b/3Primary endpoint met in Phase 3 (ORIGIN 3) in June 2025

Key Facts

Indication
IgA Nephropathy (IgAN)
Phase
Phase 2b/3
Status
Primary endpoint met in Phase 3 (ORIGIN 3) in June 2025
Company

About Vera Therapeutics

Vera Therapeutics is a clinical-stage biotech focused on developing transformative treatments for B-cell and plasma cell-driven autoimmune diseases. Its core achievement is the successful Phase 3 ORIGIN 3 trial of atacicept in IgA nephropathy (IgAN), meeting its primary endpoint in June 2025, which sets the stage for a potential first-in-class therapy. The company's strategy leverages a deep understanding of B-cell biology to selectively target pathogenic drivers, with a lean operational model aimed at efficiently advancing its pipeline toward commercialization and addressing high unmet medical needs.

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About Vera Therapeutics

Vera Therapeutics is a clinical-stage biotech focused on developing transformative treatments for B-cell and plasma cell-driven autoimmune diseases. Its core achievement is the successful Phase 3 ORIGIN 3 trial of atacicept in IgA nephropathy (IgAN), meeting its primary endpoint in June 2025, which sets the stage for a potential first-in-class therapy. The company's strategy leverages a deep understanding of B-cell biology to selectively target pathogenic drivers, with a lean operational model aimed at efficiently advancing its pipeline toward commercialization and addressing high unmet medical needs.

View full company profile

Other IgA Nephropathy (IgAN) Drugs

DrugCompanyPhase
R1065Harbour BioMedDiscovery
TARPEYO (Nefecon)Calliditas TherapeuticsApproved
TARPEYO (Nefecon) OLECalliditas TherapeuticsPhase 3
KP104Kira PharmaceuticalsPhase 2
IFX-301InfinimmunePreclinical
FILSPARI (sparsentan)Travere TherapeuticsApproved
TelitaciceptVor BiopharmaBLA Submitted