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AAV Gene Therapy Enabler

Depletion of pre-existing AAV neutralizing antibodies

Pre-clinical/ResearchActive

Key Facts

Indication
Depletion of pre-existing AAV neutralizing antibodies
Phase
Pre-clinical/Research
Status
Active
Company

About MediSieve

MediSieve is a private, pre-revenue biotech founded in 2014, pioneering a magnetic blood filtration platform. Its core technology involves functionalizing magnetic beads to bind specific targets in the blood, which are then removed extracorporeally via a magnetic filter. The pipeline targets acute hyperinflammation (e.g., sepsis, CRS), severe malaria, and enabling AAV gene therapies by depleting neutralizing antibodies. The company represents a novel therapeutic device approach in hematology and critical care.

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