Vunthera

Cytomegalovirus is a highly prevalent herpesvirus, with 40 to 80% of the adults having encountered a primary CMV infection in their life, depending on the geographical location. Like other herpesviruses, CMV establishes a harmless but life-long latent infection, hiding with low frequency in monocytes and hematopoietic stem cells. Occasionally, a fraction of these latently infected cells gets reactivated. In healthy individuals, such secondary infections are rapidly dealt with by the immune sy...