Charles River Laboratories

Charles River Laboratories

CRL
Is this your company? Claim your profile to update info and connect with investors.
Claim profile

CRL · Stock Price

USD 181.68+42.89 (+30.90%)
Market Cap: $8.7B

Historical price data

Market Cap: $8.7BPipeline: 1 drugPatents: 20Founded: 1947Employees: 20,000+HQ: Wilmington, United States

Overview

Charles River Laboratories operates as a foundational partner in the biopharmaceutical ecosystem, offering an integrated suite of services spanning research models, discovery, safety assessment, and manufacturing support. The company has established itself as a bellwether for industry R&D activity, with a notable 80% of FDA-approved drugs over the past five years having utilized its services. Its strategy focuses on expanding capabilities in high-growth areas like cell and gene therapy, investing in New Approach Methodologies (NAMs) to reduce animal testing, and leveraging its global scale to provide end-to-end solutions that streamline client pathways to regulatory submission.

OncologyNeuroscienceImmunologyRare DiseaseCell & Gene Therapy

Technology Platform

An integrated suite of services and technologies spanning research models (GEMS), integrated drug discovery, specialized platforms (Retrogenix, SAMiRNA, Porcilon), IND-enabling safety assessment, New Approach Methodologies (NAMs), and biologics & cell/gene therapy CDMO manufacturing.

Pipeline

1
1 drug in pipeline
DrugIndicationStageWatch
[14C]-bilastineHealthyPhase 1

Funding History

2
Total raised:$572M
Debt$500M
IPO$72M

Opportunities

The company is poised to capitalize on the rapid growth in complex therapeutic modalities like cell and gene therapies, requiring specialized CDMO services.
Furthermore, its leadership in developing New Approach Methodologies (NAMs) positions it at the forefront of a regulatory and scientific shift towards alternative testing strategies, opening new markets and reinforcing its scientific credibility.

Risk Factors

Revenue is highly correlated with biotech funding cycles, creating volatility during market downturns.
The core business also faces long-term regulatory and societal pressure to reduce animal testing, while operational risks include supply chain challenges for critical models like non-human primates and intense competition across all service lines.

Competitive Landscape

Charles River competes with large, full-service CROs like Labcorp and IQVIA in discovery/preclinical, specialized CDMOs like Lonza in manufacturing, and niche players in research models. Its key differentiators are its unique integrated model from models to CDMO, global scale, and a strong regulatory track record supporting a vast majority of recent drug approvals.

Company Timeline

1947Founded

Founded in Wilmington, United States

2000IPO

IPO — $72.0M

2017Debt

Debt: $500.0M