Sensorion

Sensorion

ALSEN.PA
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ALSEN.PA · Stock Price

EUR 0.41+0.01 (+1.50%)
Market Cap: $259.8M

Historical price data

Overview

Sensorion's mission is to address the profound unmet medical need in hearing loss through a three-pillar strategy: Restore hearing via gene therapy for genetic disorders, Treat acute hearing loss with small molecules, and Prevent hearing loss in various settings. The company has established a proprietary R&D platform and advanced its lead gene therapy candidate, OTOF-GT, into a Phase 1/2 trial for otoferlin deficiency. Its strategy combines internal development with strategic partnerships to build a comprehensive portfolio targeting both rare and common forms of auditory impairment.

OtologyHearing LossInner Ear Disorders

Technology Platform

An integrated R&D platform combining deep inner ear biology expertise to develop both AAV-based gene therapies for targeted cochlear delivery and small molecules for hair cell and neuron protection/repair.

Pipeline

6
6 drugs in pipeline1 in Phase 3
DrugIndicationStageWatch
SENS-401 + SENS-401Severe Sudden Sensorineural Hearing LossPhase 2/3
SENS-401 (R-Azasetron Besylate)Hearing LossPhase 2
SENS-111 100mg + SENS-111 200mg + Placebo Oral TabletAcute Unilateral Vestibulopathy (AUV)Phase 2
SENS-401 (R-Azasetron Besylate)Hearing Loss OtotoxicPhase 2
SENS-218Inner Ear DiseasesPhase 1

Funding History

4
Total raised:$78M
PIPE$25M
IPO$30M
Series B$15M
Series A$8M

Opportunities

Sensorion addresses a massive, underserved global market with no approved disease-modifying drugs.
Success with its lead OTOF-GT gene therapy could establish a new treatment paradigm for genetic hearing loss and validate its platform for broader applications.
Positive data from its SENS-401 program in cisplatin-induced ototoxicity would tap into a clear preventative need in oncology supportive care.

Risk Factors

The company faces high clinical trial risk with its lead programs, financial risk as a pre-revenue entity requiring further capital raises, and intensifying competition from larger biopharma companies now entering the otology space.
Regulatory hurdles and proving cost-effectiveness for novel therapies present additional commercialization risks.

Competitive Landscape

Sensorion is a European pioneer but faces competition from US-based firms like Akouos (Eli Lilly) and Decibel Therapeutics in gene therapy. The small molecule landscape has seen setbacks, but new entrants continue. The company's focused expertise and dual-platform strategy are differentiators, but it competes with entities possessing greater financial resources.