Sana Biotechnology

Sana Biotechnology

SANAApproved
Seattle, United StatesFounded 2020sana.com

Sana Biotechnology is at the forefront of developing a new class of engineered cell therapies designed to be broadly accessible. The company is advancing a pipeline of innovative candidates, including stem cell-derived pancreatic islets for type 1 diabetes and in vivo CAR T therapies for B-cell malignancies and autoimmune disorders. With a seasoned leadership team and a focus on overcoming key challenges in cell therapy like immune rejection and scalable manufacturing, Sana aims to deliver durable, one-time cures for a wide range of serious diseases.

Market Cap
$830.0M
Founded
2020
Focus
RNA & Gene TherapyCell & Gene Therapy

SANA · Stock Price

USD 3.113.95 (-55.95%)

Historical price data

AI Company Overview

Sana Biotechnology is at the forefront of developing a new class of engineered cell therapies designed to be broadly accessible. The company is advancing a pipeline of innovative candidates, including stem cell-derived pancreatic islets for type 1 diabetes and in vivo CAR T therapies for B-cell malignancies and autoimmune disorders. With a seasoned leadership team and a focus on overcoming key challenges in cell therapy like immune rejection and scalable manufacturing, Sana aims to deliver durable, one-time cures for a wide range of serious diseases.

Technology Platform

Sana develops two core platforms: 1) An ex vivo 'Hypoimmune' platform to create universal cell therapies that evade immune rejection, and 2) An in vivo 'Fusogen' platform to genetically engineer a patient's cells directly inside the body.

Pipeline Snapshot

4

4 drugs in pipeline

DrugIndicationStage
SC291Lupus ErythematosusPhase 1
SC262Non Hodgkin's LymphomaPhase 1
SC291Non Hodgkin LymphomaPhase 1
UP421Type1diabetesPhase 1

Funding History

3

Total raised: $2.0B

IPO$587.6MUndisclosedFeb 4, 2021
Series B$700MCanada Pension Plan Investment BoardJun 15, 2020
Series A$700MARCH Venture PartnersAug 15, 2019

FDA Approved Drugs

1
GRANISETRON HYDROCHLORIDEANDAMar 17, 2025

Opportunities

Sana's platforms, if validated, offer massive expansion opportunities.
The hypoimmune technology could be applied to replace any cell type, opening new therapeutic areas in neurology (e.g., Parkinson's), cardiology, and liver disease.
The in vivo fusogen platform could be adapted to target different cell types and deliver various genetic payloads, creating a pipeline of in vivo therapies beyond CAR-T.

Risk Factors

The company faces significant clinical and technological risks as its novel platforms enter human testing.
High cash burn necessitates future capital raises, potentially diluting shareholders.
It operates in intensely competitive fields against well-funded rivals with alternative technological approaches.

Competitive Landscape

Sana competes with Vertex and CRISPR in diabetes cell therapy, and with numerous biotechs (e.g., Intellia, Beam, Allogene) in gene editing and allogeneic cell therapy. Its key differentiation is the combined focus on solving immune rejection (hypoimmune) and enabling targeted in vivo delivery (fusogen) to create more accessible and durable cell medicines.

Publications
20
Pipeline
4
FDA Approvals
1

Company Info

TypeTherapeutics
Founded2020
LocationSeattle, United States
StageApproved
RevenuePre-revenue

Trading

TickerSANA
ExchangeNASDAQ

Contact

Therapeutic Areas

OncologyAutoimmune DiseasesMetabolic Diseases
SIMILAR COMPANIES
BASi Research Products
BASi Research Products
Pre-clinical · West Lafayette
Bay BioSciences
Bay BioSciences
Pre-clinical · San Francisco
EydisBio
EydisBio
Pre-clinical · Cambridge
3Spine
3Spine
Pre-clinical · Memphis
Belcher Pharmaceuticals
Belcher Pharmaceuticals
Pre-clinical · Miami
Is this your company?

Claim your profile to update information, add pipeline data, and connect with investors.

Claim profile