MeiraGTx
MGTXMGTX · Stock Price
Historical price data
Overview
MeiraGTx is a clinical-stage biotech focused on translating advanced genetic medicine into transformative therapies for diseases with high unmet need. Its strategy is built on a fully integrated platform combining novel vector engineering, precision gene control via its riboswitch technology, and in-house GMP manufacturing. Key achievements include a late-stage pipeline with Breakthrough Therapy designation for its xerostomia program and a major strategic collaboration with Eli Lilly in ophthalmology, positioning the company for significant value inflection.
Technology Platform
Proprietary platform featuring optimized AAV vector engineering, tissue-specific promoters, and a transformative riboswitch gene regulation system enabling precise, oral small molecule-controlled transgene expression for a wide range of diseases.
Pipeline
7| Drug | Indication | Stage | Watch |
|---|---|---|---|
| AAV RPE65 | Leber Congenital Amaurosis | Phase 1/2 | |
| AAV - CNGB3 | Achromatopsia | Phase 1/2 | |
| adeno-associated virus vector AAV- CNGA3 | Achromatopsia | Phase 1/2 | |
| AAV2hAQP1 | Squamous Cell Head and Neck Cancer | Phase 1 | |
| AAV2hAQP1: 1 x 10^11 vg/gland (single gland) + AAV2hAQP1: 3 ... | Radiation-Induced Parotid Gland Hypofunction | Phase 1 |
Funding History
2Opportunities
Risk Factors
Competitive Landscape
MeiraGTx competes in ophthalmology with established gene therapy players like Roche/Spark, but its riboswitch platform is a key differentiator with few direct peers. The Eli Lilly partnership validates its ophthalmology approach. In large chronic diseases, its riboswitch technology positions it against major pharma companies but with a fundamentally different, potentially disruptive modality.
Competitors
Company Timeline
Founded in New York, United States
Series B: $45.0M
IPO — $75.0M