Precigen
PGENPGEN · Stock Price
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Overview
Precigen is a commercial-stage biopharmaceutical company focused on developing precision gene and cell therapies for immuno-oncology, autoimmune disorders, and infectious diseases. The company achieved a critical inflection point with the FDA approval of PAPZIMEOS in August 2025 for recurrent respiratory papillomatosis (RRP). Its strategy is built on two proprietary technology platforms—AdenoVerse® for viral vector gene delivery and UltraCAR-T® for next-generation cell therapy—designed to overcome key limitations in the field and create a sustainable pipeline of advanced therapeutics.
Technology Platform
Precigen's core technologies are the AdenoVerse® platform, a proprietary gorilla adenovector system for in vivo gene delivery with low seroprevalence and repeat-dosing capability, and the UltraCAR-T® platform, a non-viral, rapid-manufacturing CAR-T cell therapy system designed for enhanced persistence and solid tumor activity.
Pipeline
8| Drug | Indication | Stage | Watch |
|---|---|---|---|
| Zopapogene imadenovec (Zopa) | Recurrent Respiratory Papillomatosis | Approved | |
| PRGN-2009 plus Pembrolizumab + Pembrolizumab alone | Cervical Cancer | Phase 2 | |
| PRGN-2012 - Phase I; Dose Level 1 + PRGN-2012 - Phase I; Dos... | Recurrent Respiratory Papillomatosis | Phase 1/2 | |
| AG019 - Low Dose + Teplizumab + Placebo-AG019 + Placebo-Tepl... | Diabetes type1 | Phase 1/2 | |
| INXN-4001 | Heart Failure | Phase 1 |
Funding History
2Company Timeline
Founded in Germantown, United States
Grant: $200.0K
Debt: $50.0M