Novocure

Novocure

NVCRPhase 3
Saint Helier, JerseyFounded 2000novocure.com

Founded in 2000 by Professor Yoram Palti, Novocure has developed a unique, physics-based cancer treatment platform that targets solid tumors with electric fields, offering a treatment option with a distinct side-effect profile. Its first commercial success came with FDA approvals for glioblastoma in 2011 and 2015, and it recently secured a landmark approval for pancreatic cancer in 2024. The company's strategy centers on broadening the clinical validation of TTFields across multiple cancer types through a robust late-stage clinical pipeline.

Market Cap
$2.4B
Founded
2000
Employees
1,300+
Focus
OncologyMedical Devices

NVCR ยท Stock Price

USD 20.951.05 (-4.77%)

Historical price data

AI Company Overview

Founded in 2000 by Professor Yoram Palti, Novocure has developed a unique, physics-based cancer treatment platform that targets solid tumors with electric fields, offering a treatment option with a distinct side-effect profile. Its first commercial success came with FDA approvals for glioblastoma in 2011 and 2015, and it recently secured a landmark approval for pancreatic cancer in 2024. The company's strategy centers on broadening the clinical validation of TTFields across multiple cancer types through a robust late-stage clinical pipeline.

Technology Platform

Tumor Treating Fields (TTFields): A non-invasive, anti-mitotic cancer therapy that uses low-intensity, alternating electric fields tuned to specific frequencies to disrupt cell division in solid tumors.

Pipeline Snapshot

33

33 drugs in pipeline, 5 in Phase 3

DrugIndicationStage
Gemcitabine + nab paclitaxelPancreas AdenocarcinomaPhase 3
TemozolomideGlioblastoma MultiformePhase 3
Pembrolizumab + Platinum based chemotherapyMetastatic Non-small Cell Lung CancerPhase 3
Immune checkpoint inhibitors or docetaxelNonsmall Cell Lung CancerPhase 3
PaclitaxelOvarian CancerPhase 3

Funding History

4

Total raised: $205M

IPO$125MUndisclosedOct 9, 2015
Series C$45MDeerfield ManagementJun 15, 2010
Series B$25MWellington PartnersJun 15, 2007
Series A$10MIndex VenturesJun 15, 2004

Opportunities

Significant growth opportunities exist in expanding TTFields into large solid tumor indications like non-small cell lung cancer and ovarian cancer, where Phase 3 trials are underway.
The recent FDA approval for locally advanced pancreatic cancer provides an immediate new commercial market.
Further lifecycle management and combination studies with emerging therapies (e.g., immunotherapies) could enhance efficacy and adoption.

Risk Factors

Key risks include the potential for clinical trial failures in ongoing Phase 3 studies, which are critical for future growth.
Commercial execution risks involve driving physician adoption and securing reimbursement for new indications.
The company also faces competition from advancing drug and radiation therapies in its target cancers.

Competitive Landscape

Novocure's TTFields therapy has no direct modality competitor, competing instead with standard drug, radiation, and surgical approaches in each cancer type. Its primary differentiation is its non-invasive mechanism and favorable safety profile, allowing for combination therapy. Major competitors include large pharma companies developing oncology drugs (e.g., Merck, Roche, AstraZeneca) and other device or radiotherapy firms.

Publications
20
Patents
20
Pipeline
33

Company Info

TypeTherapeutics
Founded2000
Employees1,300+
LocationSaint Helier, Jersey
StagePhase 3
RevenueRevenue Generating

Trading

TickerNVCR
ExchangeNASDAQ

Therapeutic Areas

OncologyGlioblastomaPancreatic CancerNon-Small Cell Lung CancerOvarian CancerGastric CancerMesothelioma

Partners

American Brain Tumor AssociationCancerCareCancer Support CommunityCaregiver Action NetworkEndBrainCancer InitiativeHead for the CureBrains for the CureMesothelioma Applied Research FoundationMusella FoundationNational Brain Tumor SocietyOurBrainBankStacheStrong
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