Inhibrx Biosciences

Inhibrx Biosciences

INBX
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INBX · Stock Price

USD 124.52+113.34 (+1014.27%)
Market Cap: $1.8B

Historical price data

Market Cap: $1.8BPipeline: 6 drugs (1 Phase 3)Patents: 20Founded: 2010Employees: 50-75HQ: La Jolla, United States

Overview

Inhibrx Biosciences is a public, clinical-stage biotech focused on developing differentiated biologics for high-need oncology indications. Its core innovation is a versatile single-domain antibody (sdAb) platform that enables the creation of multi-valent, conditionally active molecules with potential advantages over conventional antibodies. The company's strategy centers on advancing its two lead clinical assets, a tetravalent DR5 agonist for sarcoma and a hexavalent OX40 agonist for solid tumors, while leveraging its lean, protein-engineering expertise to create future pipeline candidates.

OncologyOrphan Diseases

Technology Platform

Proprietary single-domain antibody (sdAb) platform enabling the engineering of multi-valent, conditionally active biologic therapeutics with superior tissue penetration and tailored mechanisms of action.

Pipeline

6
6 drugs in pipeline1 in Phase 3
DrugIndicationStageWatch
INBRX-106 + PembrolizumabHead and Neck Squamous Cell Carcinoma (HNSCC)Phase 2/3
INBRX-109 + PlaceboConventional ChondrosarcomaPhase 2
Pembrolizumab + INBRX-106Triple Negative Breast CancerPhase 2
INBRX-105 - PDL1x41BB antibody + PembrolizumabMetastatic Solid TumorsPhase 1
INBRX-101/rhAAT-FcAlpha-1 Antitrypsin DeficiencyPhase 1

Funding History

4
Total raised:$350M
IPO$150M
Series C$120M
Series B$60M
Series A$20M

Opportunities

Validating its multi-valent sdAb platform through lead clinical programs could unlock significant value in high-need oncology markets like sarcoma and immuno-oncology.
Success may enable expansion into broader solid tumor indications and the generation of new pipeline candidates targeting other agonistic pathways.

Risk Factors

High clinical failure risk for its two lead assets, concentrated pipeline post-spin-off, finite cash runway requiring future financing, and intense competition in both the DR5 and OX40 agonist landscapes from larger, better-resourced companies.

Competitive Landscape

Faces competition in DR5 agonists from legacy failed programs and new modalities, and in OX40 from numerous big pharma and biotech candidates. Differentiates through its platform's ability to create conditionally active, multi-valent molecules designed for superior potency and safety.

Company Timeline

2010Founded

Founded in La Jolla, United States

2016Series B

Series B: $60.0M

2018Series C

Series C: $120.0M

2020IPO

IPO — $150.0M