Inhibrx Biosciences
INBXPhase 3Inhibrx leverages its proprietary sdAb platform to create differentiated, multi-specific protein therapeutics designed to overcome the limitations of conventional antibodies. The company's pipeline includes multiple clinical-stage assets targeting oncology and rare diseases, with strategic partnerships in place with major pharmaceutical companies. Inhibrx's approach focuses on optimizing pharmacokinetics, tissue penetration, and manufacturability to develop best-in-class therapies for complex biological targets.
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AI Company Overview
Inhibrx leverages its proprietary sdAb platform to create differentiated, multi-specific protein therapeutics designed to overcome the limitations of conventional antibodies. The company's pipeline includes multiple clinical-stage assets targeting oncology and rare diseases, with strategic partnerships in place with major pharmaceutical companies. Inhibrx's approach focuses on optimizing pharmacokinetics, tissue penetration, and manufacturability to develop best-in-class therapies for complex biological targets.
Technology Platform
Proprietary platform for engineering single-domain antibody (sdAb) fragments into multi-specific, Fc-fused protein therapeutics with optimized pharmacokinetics and tissue penetration.
Pipeline Snapshot
66 drugs in pipeline, 1 in Phase 3
| Drug | Indication | Stage | Watch |
|---|---|---|---|
| INBRX-106 + Pembrolizumab | Head and Neck Squamous Cell Carcinoma (HNSCC) | Phase 2/3 | |
| INBRX-109 + Placebo | Conventional Chondrosarcoma | Phase 2 | |
| Pembrolizumab + INBRX-106 | Triple Negative Breast Cancer | Phase 2 | |
| INBRX-105 - PDL1x41BB antibody + Pembrolizumab | Metastatic Solid Tumors | Phase 1 | |
| INBRX-101/rhAAT-Fc | Alpha-1 Antitrypsin Deficiency | Phase 1 |
Funding History
4Total raised: $350M
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Competitive Landscape
Faces competition in AATD from plasma-derived therapy leaders (Grifols, Takeda, CSL Behring) and novel modality companies. In oncology, competes with numerous biopharma firms developing PD-1/L1 and costimulatory agonists. Platform competes with other fragment-based technology companies like Sanofi (Ablynx) and Molecular Partners.
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