Lantheus Holdings

Lantheus Holdings

LNTH
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LNTH · Stock Price

USD 91.00+9.26 (+11.33%)
Market Cap: $6.0B

Historical price data

Market Cap: $6.0BPipeline: 40 drugs (8 Phase 3)Founded: 1956Employees: 1000-5000HQ: North Billerica, United States

Overview

Lantheus Holdings is a commercial leader in the radiopharmaceutical space, built on a vertically integrated model spanning discovery through global sales. Its strategy is anchored by the commercial success of PYLARIFY®, a leading PSMA PET imaging agent for prostate cancer, and DEFINITY®, an established ultrasound contrast agent. The company is advancing a deep pipeline of approximately 40 programs, targeting expansion in radiopharmaceutical oncology and diagnostics, while leveraging its robust manufacturing and commercial infrastructure to drive growth. With a market cap of ~$4.8B, Lantheus is positioned as a key consolidator and innovator in the high-growth targeted radiopharmaceutical sector.

OncologyCardiovascular

Technology Platform

A fully integrated radiopharmaceutical platform encompassing targeted ligand discovery, radiochemistry, end-to-end manufacturing of isotopes and drug products, and a global commercial network, all aligned under the 'Find, Fight, Follow®' strategy.

Pipeline

40
40 drugs in pipeline8 in Phase 3
DrugIndicationStageWatch
Piflufolastat F 18 Intravenous Solution [PYLARIFY]Prostate CancerApproved
3D HI and SHI of UCABreast CancerApproved
Definity® Vial for (Perflutren Lipid Microsphere) Injectable...Ventricular Ejection FractionApproved
DefinityPulmonary Heart DiseaseApproved
Technetium Tc99m SestamibiDiabetes Mellitus, Type 2Approved

Funding History

2
Total raised:$286M
Debt$200M
IPO$86M

FDA Approved Drugs

8
NEURACEQNDAMar 19, 2014
DEFINITY RTNDAJul 31, 2001
DEFINITYNDAJul 31, 2001

Opportunities

The primary opportunity lies in leveraging the commercial success of PYLARIFY to launch a complementary therapeutic, PNT2001, creating a dominant 'Find and Fight' franchise in prostate cancer.
Further expansion into large new markets like neuroendocrine tumors (via SSTR programs) and pan-cancer imaging/treatment (via FAP programs) provides significant long-term growth runways.

Risk Factors

Key risks include clinical failure of the late-stage therapeutic pipeline, intensifying competition from large pharmaceutical companies, and the operational complexities of manufacturing and distributing short-half-life radiopharmaceuticals.
Revenue concentration in PYLARIFY also presents a dependency risk.

Competitive Landscape

Lantheus competes in PSMA PET diagnostics primarily against Telix's Illuccix®, holding a strong duopoly position. In radiopharmaceutical therapeutics, it faces formidable competition from Novartis's approved Pluvicto® and other well-funded entities like Eli Lilly (Point Biopharma) and Bayer. Its vertically integrated platform and diagnostic-therapeutic synergy are key differentiators.

Company Timeline

1956Founded

Founded in North Billerica, United States

2001FDA Approval

FDA Approval: DEFINITY RT

2001FDA Approval

FDA Approval: DEFINITY

2014FDA Approval

FDA Approval: NEURACEQ

2015IPO

IPO — $86.0M

2021Debt

Debt: $200.0M