ITB Med

ITB Med

Stockholm, Sweden· Est.
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Private Company

Total funding raised: $10.5M

Overview

ITB-MED is a clinical-stage biotech pioneering a transformative approach to organ transplantation and autoimmunity. Its central mission is to induce immune tolerance, freeing patients from lifelong immunosuppression, which could dramatically improve health outcomes, quality of life, and reduce long-term healthcare costs. The company's pipeline is built around its proprietary CD2 antagonist, TCD601, with multiple programs in transplantation and autoimmunity, several of which have advanced into clinical development. With a seasoned leadership team and operations spanning two continents, ITB-MED is positioning itself as a key player in the next generation of immunomodulatory therapies.

TransplantationAutoimmunity

Technology Platform

Immune modulation via antagonistic CD2-directed monoclonal antibody (TCD601/siplizumab) designed to deplete pathogenic T-cell subsets and promote a tolerogenic environment.

Funding History

2
Total raised:$10.5M
Series A$8M
Seed$2.5M

Opportunities

Success in inducing transplantation tolerance could disrupt the multi-billion dollar chronic immunosuppressant market by offering a potentially curative, one-time treatment.
The CD2 platform also presents a significant expansion opportunity into large autoimmune disease markets like Type-1 Diabetes and ALS, where disease-modifying therapies are urgently needed.

Risk Factors

High risk of clinical failure in achieving durable, broad-based immune tolerance in controlled trials.
Significant regulatory uncertainty surrounds the development pathway for a tolerance-inducing product.
The company faces intense competition from other biopharma firms exploring tolerance and immunomodulation, and is dependent on external financing to advance its broad pipeline.

Competitive Landscape

ITB-MED operates in a competitive but nascent field. It faces competition from other biotechs (e.g., Talaris Therapeutics, Sangamo Therapeutics) and large pharma companies exploring various tolerance strategies, including cell therapies, co-stimulation blockade, and other biologic agents. Its differentiation lies in its specific focus on the CD2 pathway and its direct clinical programs aimed at complete immunosuppression withdrawal.