Biotrial

Biotrial

Rennes, France· Est.
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Private Company

Total funding raised: $56M

Overview

Biotrial is a well-established, France-based CRO with over 35 years of experience in drug development services. It provides an integrated suite of offerings spanning preclinical pharmacology (efficacy, safety, PK), clinical development (notably Phase I studies in healthy volunteers and special populations), and specialized support services like biometrics, bioanalysis, and data science. The company operates globally with Clinical Pharmacology Units in the US and France, positioning it as a partner for biotech and pharma companies seeking to de-risk and accelerate their R&D programs.

Clinical Research

Technology Platform

Integrated CRO service platform encompassing Preclinical Pharmacology (in vitro/in vivo efficacy, safety, PK), Clinical Development with owned Phase I units, and specialized support labs (Bioanalysis, Biometrics, ECG, CNS & Imaging Core Lab). Enhanced by Data Science/AI capabilities via acquisition of ExactCure.

Pipeline

7
7 drugs in pipeline
DrugIndicationStageWatch
EXS21546Advanced Solid TumoursPhase 1/2
Phase 1, SQY51 + Phase 2a, SQY51 (cohort 1) + Phase 2a, SQY5...Duchenne Muscular DystrophyPhase 1/2
LPH-5 + PlaceboSafety IssuesPhase 1
Binimetinib Oral TabletMelanomaPhase 1
ITF2357Hepatic ImpairmentPhase 1

Funding History

4
Total raised:$56M
Debt$15M
Debt$8M
Grant$8M
Series B$25M

Opportunities

Strong demand for integrated early-phase (preclinical to Phase I) services from a growing biotech sector.
Niche capabilities in CNS, cardiac safety, and data science present high-value service differentiators.
Global footprint allows capture of international clinical trials.

Risk Factors

High competition in the CRO market from large global players and niche specialists.
Operational risks include potential adverse clinical events or regulatory compliance failures.
Revenue dependency on client R&D spending, which can be cyclical.

Competitive Landscape

Operates in the highly competitive global CRO market, competing against large public players (e.g., IQVIA, LabCorp, Parexel) and many specialized mid-sized and boutique CROs. Differentiates through integrated early-phase services, owned clinical pharmacology units, and specialized core labs (e.g., CNS & Imaging).