Affibody

Affibody

Solna, Sweden· Est.
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Private Company

Total funding raised: $210M

Overview

Affibody is a clinical-stage biotech pioneering a new generation of targeted radioligand therapies (RLTs) for oncology using its proprietary Affibody® molecule platform. The company's strategy focuses on targets and cancer indications with high unmet need where its small, engineered protein scaffolds offer potential competitive advantages in tumor penetration and clearance. Beyond its core oncology pipeline, Affibody generates value through partnership programs in immunology and has established key collaborations for radiopharmaceutical supply and development. With a strong scientific foundation, a deep pipeline, and a seasoned team, Affibody is positioned as a notable player in the expanding radiopharmaceutical therapeutics field.

OncologyImmunology

Technology Platform

Proprietary Affibody® platform: small (6 kDa), engineered protein scaffolds used to create precision-targeting molecules for radioligand therapies (RLTs). Offers advantages in tissue penetration, rapid clearance, and stability.

Funding History

3
Total raised:$210M
Series C$110M
Series B$75M
Series A$25M

Opportunities

The global radiopharmaceutical therapeutics market is expanding rapidly, offering a multi-billion dollar opportunity for novel, targeted therapies.
Affibody's platform technology, with its potential for superior tumor targeting and pharmacokinetics, could capture significant value in treating solid tumors with high unmet need.
Successful partnered immunology programs provide near-term validation and non-dilutive funding.

Risk Factors

The company faces significant clinical development risk inherent in novel drug platforms, alongside intense competition in the radiopharmaceutical space from large pharma.
Operational execution risks include securing reliable, costly supplies of medical isotopes like Lutetium-177 and navigating complex radiopharmaceutical manufacturing and logistics.

Competitive Landscape

Affibody competes in the radiopharmaceutical space with large players like Novartis (Pluvicto, Lutathera) and a growing number of biotechs (e.g., RayzeBio, Fusion Pharmaceuticals). Its competitive edge is based on the small size and pharmacokinetic profile of its Affibody molecules, which may offer advantages over antibody-based RLTs. In immunology, izokibep competes with established IL-17 inhibitors like Cosentyx.