iota Biosciences

Executive Summary

iota Biosciences is a bioelectronics company developing ultrasound-powered, millimeter-scale implantable devices for diagnostic and therapeutic applications. Founded in 2017 based on technology from UC Berkeley, the company focuses on neurological and urological conditions. As a subsidiary of Astellas Pharma, it leverages the parent company's resources for development and commercialization. Its platform enables minimally invasive, targeted neuromodulation without batteries, a key differentiator in the implantable device space. The lead program targets overactive bladder, with potential expansion into chronic pain and other neurological disorders.

Upcoming Catalysts (preview)

• Q4 2026Initiation of pivotal clinical trial for overactive bladder therapy70% success
• Q3 2026Publication of preclinical data in chronic pain indication80% success
• H2 2026Strategic partnership for technology platform in neurology60% success