DASI Simulations

Executive Summary

DASI Simulations is a Boston-based private medtech company developing AI-powered computational simulations to plan structural heart procedures, with an initial focus on transcatheter aortic valve replacement (TAVR). Founded in 2020, the company's platform uses patient-specific imaging data to create predictive models that help interventional cardiologists assess risks and optimize surgical strategies. By generating personalized, data-driven simulations, DASI aims to reduce procedural complications and improve patient outcomes. The platform addresses a critical unmet need in the rapidly expanding TAVR market, where precise planning is essential due to complex patient anatomies and the growth of less invasive approaches. While DASI Simulations is still in an early stage, its technology has the potential to become a standard tool in structural heart planning if it can demonstrate clinical utility and cost-effectiveness. The company is expected to seek regulatory clearance and generate clinical evidence to support adoption. Key risks include competition from established imaging and planning solutions, as well as the regulatory pathway for AI-based medical devices. Overall, DASI Simulations represents a promising but early-stage opportunity in the digital health and structural heart space.

Upcoming Catalysts (preview)

• H2 2026FDA 510(k) clearance for TAVR simulation module60% success
• Q3 2026Publication of retrospective clinical validation study70% success
• Q4 2026Strategic partnership with a major hospital system or medical device company40% success