vormatrogine

Phase 3Recruiting

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Interest: 44/100

Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

✓

Phase 2

Phase 3

Approved

Indication / Disease

Epilepsy, Tonic-Clonic

Conditions

Epilepsy, Tonic-Clonic, Focal Seizure, Primary Generalized Seizure

Trial Timeline

Oct 27, 2025 → Dec 31, 2028

NCT ID

NCT07287163

About vormatrogine

vormatrogine is a phase 3 stage product being developed by Praxis Precision Medicines for Epilepsy, Tonic-Clonic. The current trial status is recruiting. This product is registered under clinical trial identifier NCT07287163. Target conditions include Epilepsy, Tonic-Clonic, Focal Seizure, Primary Generalized Seizure.

What happened to similar drugs?

20 of 20 similar drugs in Epilepsy, Tonic-Clonic were approved

Approved (20) Terminated (6) Active (0)

✅ZonegranEisaiApproved

✅Perampanel + PlaceboEisaiApproved

✅perampanelEisaiApproved

✅Perampanel Oral TabletEisaiApproved

✅PerampanelEisaiApproved

✅zonisamide low dose group + zonisamide high dose groupEisaiApproved

✅Zonisamide at targeted daily doses of 100-500 mg/day + Placebo administered to match targeted daily doses of 100-500 mg/dayEisaiApproved

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (1)

NCT ID	Phase	Status	Start	Completion	Indication
NCT07287163	Phase 3	Recruiting	Oct 27, 2025	Dec 31, 2028	Epilepsy, Tonic-Clonic

Competing Products

20 competing products in Epilepsy, Tonic-Clonic

See all competitors

Product	Company	Stage	Hype Score
perampanel	Eisai	Phase 2	35
Lacosamide	UCB	Phase 3	40
Zonisamide + Placebo	Eisai	Phase 3	32
Zonegran	Eisai	Approved	35
perampanel + perampanel	Eisai	Phase 1	29
Perampanel + Placebo	Eisai	Approved	35
perampanel	Eisai	Approved	35
E2007 + Placebo	Eisai	Phase 2	35
Placebo + Rufinamide	Eisai	Phase 3	40
E2007 (perampanel) + Placebo	Eisai	Phase 2	35
Perampanel Oral Tablet	Eisai	Approved	43
perampanel	Eisai	Phase 3	40
Perampanel	Eisai	Pre-clinical	26
Zonisamide + Carbamazepine	Eisai	Phase 3	40
Perampanel	Eisai	Approved	43
Perampanel and Microgynon-30 + Perampanel and Microgynon-30	Eisai	Phase 1	29
Perampanel	Eisai	Phase 2	35
Zonisamide + Placebo	Eisai	Phase 3	40
zonisamide low dose group + zonisamide high dose group	Eisai	Approved	43
E2007 + E2007 + Placebo	Eisai	Phase 2	35