Vatiquinone
Phase 2/3Terminated 0 watching 0 views this week📈 Rising
62
Development Stage
✓
Pre-clinical✓
Phase 13
Phase 24
Phase 35
ApprovedIndication / Disease
Mitochondrial Diseases
Conditions
Mitochondrial Diseases, Drug Resistant Epilepsy, Leigh Disease, Leigh Syndrome, Mitochondrial Encephalopathy (MELAS), Pontocerebellar Hypoplasia Type 6 (PCH6), Alpers Disease, Alpers Syndrome
Trial Timeline
Sep 28, 2020 → Dec 27, 2023
NCT ID
NCT04378075About Vatiquinone
Vatiquinone is a phase 2/3 stage product being developed by PTC Therapeutics for Mitochondrial Diseases. The current trial status is terminated. This product is registered under clinical trial identifier NCT04378075. Target conditions include Mitochondrial Diseases, Drug Resistant Epilepsy, Leigh Disease.
Hype Score Breakdown
Clinical
22
Activity
15
Company
7
Novelty
7
Community
8
Clinical Trials (5)
| NCT ID | Phase | Status |
|---|---|---|
| NCT07159139 | Pre-clinical | Active |
| NCT05515536 | Phase 3 | Active |
| NCT05485987 | Phase 2 | Completed |
| NCT05218655 | Phase 3 | Completed |
| NCT04378075 | Phase 2/3 | Terminated |
Competing Products
13 competing products in Mitochondrial Diseases
| Product | Company | Stage | Hype Score |
|---|---|---|---|
| REN001 | OnKure Therapeutics | Phase 1 | 25 |
| Mavodelpar + Placebo | OnKure Therapeutics | Phase 2 | 44 |
| REN001 | OnKure Therapeutics | Phase 2/3 | 57 |
| Bocidelpar + Placebo | Astellas Pharma | Phase 2 | 52 |
| Omaveloxolone capsules, 2.5 mg + omaveloxolone capsules, 5 mg + omaveloxolone capsules, 10 mg + Placebo capsules + omaveloxolone capsules, 20 mg + omaveloxolone capsules, 40 mg + omaveloxolone capsules, 80 mg + omaveloxolone capsules, 160 mg | AbbVie | Phase 2 | 52 |
| Cysteamine Bitartrate | Amgen | Phase 2 | 51 |
| Cysteamine Bitartrate | Amgen | Phase 2 | 51 |
| EPI-743 | PTC Therapeutics | Pre-clinical | 20 |
| RG2133 (2',3',5'-tri-O-acetyluridine) | Repligen | Phase 1 | 30 |
| Vatiquinone | PTC Therapeutics | Pre-clinical | 20 |
| Vatiquinone | PTC Therapeutics | Phase 3 | 74 |
| Oral administration of 100 mg KH176 twice daily | Certara | Phase 2 | 47 |
| Sonlicromanol + Placebo | Certara | Phase 2 | 47 |