Tigecycline

Phase 2Completed

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Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Mycobacterium Abscessus Lung Disease

Conditions

Mycobacterium Abscessus Lung Disease, Rapidly Growing Mycobacterial Lung Disease

Trial Timeline

Apr 1, 2002 → Dec 1, 2010

NCT ID

NCT00600600

About Tigecycline

Tigecycline is a phase 2 stage product being developed by Pfizer for Mycobacterium Abscessus Lung Disease. The current trial status is completed. This product is registered under clinical trial identifier NCT00600600. Target conditions include Mycobacterium Abscessus Lung Disease, Rapidly Growing Mycobacterial Lung Disease.

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (18)

NCT ID	Phase	Status	Start	Completion	Indication
NCT01560143	Approved	Completed	Mar 1, 2012	May 1, 2012	Obesity
NCT01401023	Pre-clinical	Completed	Jul 1, 2011	Jul 1, 2013	Diarrhea
NCT01072539	Pre-clinical	Completed	May 1, 2010	Apr 1, 2015	Complicated Skin and Skin Structure Infections
NCT00827541	Pre-clinical	Completed	Aug 1, 2008	Dec 1, 2010	Intra-Abdominal Infections
NCT00575094	Phase 3	Completed	Nov 1, 2007	Mar 1, 2008	Community-Acquired Infections
NCT00419991	Approved	Completed	Jan 1, 2007	May 1, 2008	Staphylococcal Infections
NCT00406237	Phase 1	Completed	Dec 1, 2006	Mar 1, 2009	Liver Cirrhosis, Biliary
NCT00488488	Pre-clinical	Completed	Nov 1, 2006	Mar 1, 2010	Infection
NCT00376324	Phase 1	Completed	Sep 1, 2006	Oct 1, 2008	Healthy Subjects
NCT00488306	Approved	Completed	Aug 1, 2006	Aug 1, 2007	Abdominal Abscess
NCT00488761	Approved	Completed	Jul 1, 2006	Aug 1, 2007	Skin Diseases, Infectious
NCT00136201	Phase 3	Completed	Nov 1, 2005	Dec 1, 2006	Abdominal Abscess
NCT00205816	Phase 3	Completed	Jan 1, 2004	Nov 1, 2005	Bacterial Infections
NCT00079989	Phase 3	Completed	Dec 1, 2003	Nov 1, 2005	Gram-Negative Bacterial Infections
NCT00079885	Phase 3	Completed	Nov 1, 2003	Jul 1, 2005	Community Acquired Pneumonia
NCT00079976	Phase 3	Completed	Oct 1, 2003	Jun 1, 2005	Gram-Positive Bacterial Infections
NCT00081744	Phase 3	Completed	Nov 1, 2002	Aug 1, 2004	Gram-Positive Bacterial Infections
NCT00600600	Phase 2	Completed	Apr 1, 2002	Dec 1, 2010	Mycobacterium Abscessus Lung Disease

Competing Products

20 competing products in Mycobacterium Abscessus Lung Disease

See all competitors

Product	Company	Stage	Hype Score
Trifluridine	Amgen	Pre-clinical	22
clarithromycin, rifabutin	Pfizer	Approved	84
Azithromycin	Pfizer	Pre-clinical	22
Ethambutol hydrochloride + Clarithromycin + Azithromycin	Pfizer	Phase 3	76
Azithromycin	Pfizer	Pre-clinical	22
Azithromycin	Pfizer	Pre-clinical	22
Azithromycin	Pfizer	Pre-clinical	22
Azithromycin	Pfizer	Approved	84
Azithromycin + Rifabutin/rifampin	Pfizer	Approved	84
ALIS + Azithromycin + Ethambutol + ELC	Insmed	Phase 3	74
ALIS + Azithromycin + Ethambutol + ELC (matching placebo for ALIS)	Insmed	Phase 3	74
LAI plus multi-drug regimen	Insmed	Phase 2	49
Liposomal amikacin for inhalation (LAI) + placebo	Insmed	Phase 2	49
LAI (Liposomal Amikacin for Inhalation) 590 mg	Insmed	Phase 3	74
Sulbactam 25mg/kg -Durlobactam 25mg/kg (Every 6 hours) + Ceftriaxone for Injection + Amoxicillin + Azithromcyin + clarithromycin + Clofazimine + Ethambutol + Amikacin Injection + tigecycline + Imipenem + Cilastatin + Cefoxitin + Amikacin (Inhalation) + linezolid + Trimethoprim / Sulfamethoxazole + Doxycycline + moxifloxacin + bedaquiline + Rifabutin	Innoviva	Phase 2	47
Molgramostim nebulizer solution	Savara	Phase 2	47
Inhaled molgramostim + Antimycobacterial regimen	Savara	Phase 2	47
Epetraborole + Epetraborole + Placebo + Placebo	AN2 Therapeutics	Phase 2	44
SPR720 + Placebo + Open-label Standard of Care	Spero Therapeutics	Phase 2	44
RHB-204 + Placebo	RedHill Biopharma	Phase 3	69

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