tigecycline

Phase 3Completed

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Interest: 40/100

Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

✓

Phase 2

Phase 3

Approved

Indication / Disease

Community Acquired Pneumonia

Conditions

Community Acquired Pneumonia, Bacterial Pneumonia, Cross Infection

Trial Timeline

Nov 1, 2003 → Jul 1, 2005

NCT ID

NCT00079885

About tigecycline

tigecycline is a phase 3 stage product being developed by Pfizer for Community Acquired Pneumonia. The current trial status is completed. This product is registered under clinical trial identifier NCT00079885. Target conditions include Community Acquired Pneumonia, Bacterial Pneumonia, Cross Infection.

What happened to similar drugs?

2 of 12 similar drugs in Community Acquired Pneumonia were approved

Approved (2) Terminated (2) Active (8)

🔄Ceftaroline + CeftriaxonePfizerPhase 3

🔄Azithromycin microspheres 2.0 single dosePfizerPhase 3

✅IV azithromycin + ceftriaxone + oral azithromycin + IV levofloxacin + oral levofloxacinPfizerApproved

🔄Azithromycin SRPfizerPhase 3

❌Tigecycline + Tigecycline + cIAI: Ceftriaxone with metronidazole, plus if applicable aminoglycoside + CAP: Ceftriaxone, plus if applicable oral clarithromycinPfizerPhase 3

🔄tigecyclinePfizerPhase 3

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (18)

NCT ID	Phase	Status	Start	Completion	Indication
NCT01560143	Approved	Completed	Mar 1, 2012	May 1, 2012	Obesity
NCT01401023	Pre-clinical	Completed	Jul 1, 2011	Jul 1, 2013	Diarrhea
NCT01072539	Pre-clinical	Completed	May 1, 2010	Apr 1, 2015	Complicated Skin and Skin Structure Infections
NCT00827541	Pre-clinical	Completed	Aug 1, 2008	Dec 1, 2010	Intra-Abdominal Infections
NCT00575094	Phase 3	Completed	Nov 1, 2007	Mar 1, 2008	Community-Acquired Infections
NCT00419991	Approved	Completed	Jan 1, 2007	May 1, 2008	Staphylococcal Infections
NCT00406237	Phase 1	Completed	Dec 1, 2006	Mar 1, 2009	Liver Cirrhosis, Biliary
NCT00488488	Pre-clinical	Completed	Nov 1, 2006	Mar 1, 2010	Infection
NCT00376324	Phase 1	Completed	Sep 1, 2006	Oct 1, 2008	Healthy Subjects
NCT00488306	Approved	Completed	Aug 1, 2006	Aug 1, 2007	Abdominal Abscess
NCT00488761	Approved	Completed	Jul 1, 2006	Aug 1, 2007	Skin Diseases, Infectious
NCT00136201	Phase 3	Completed	Nov 1, 2005	Dec 1, 2006	Abdominal Abscess
NCT00205816	Phase 3	Completed	Jan 1, 2004	Nov 1, 2005	Bacterial Infections
NCT00079989	Phase 3	Completed	Dec 1, 2003	Nov 1, 2005	Gram-Negative Bacterial Infections
NCT00079885	Phase 3	Completed	Nov 1, 2003	Jul 1, 2005	Community Acquired Pneumonia
NCT00079976	Phase 3	Completed	Oct 1, 2003	Jun 1, 2005	Gram-Positive Bacterial Infections
NCT00081744	Phase 3	Completed	Nov 1, 2002	Aug 1, 2004	Gram-Positive Bacterial Infections
NCT00600600	Phase 2	Completed	Apr 1, 2002	Dec 1, 2010	Mycobacterium Abscessus Lung Disease

Competing Products

17 competing products in Community Acquired Pneumonia

See all competitors

Product	Company	Stage	Hype Score
ONO-5046Na + ONO-5046Na	Ono Pharmaceutical	Phase 2	35
Ticagrelor + Placebo	AstraZeneca	Phase 2	27
Ceftaroline + Ceftriaxone	Pfizer	Phase 3	40
Azithromycin microspheres 2.0 single dose	Pfizer	Phase 3	40
IV azithromycin + ceftriaxone + oral azithromycin + IV levofloxacin + oral levofloxacin	Pfizer	Approved	43
Azithromycin SR	Pfizer	Phase 3	40
Tigecycline + Tigecycline + cIAI: Ceftriaxone with metronidazole, plus if applicable aminoglycoside + CAP: Ceftriaxone, plus if applicable oral clarithromycin	Pfizer	Phase 3	32
Azithromycin SR + Amoxiclav	Pfizer	Pre-clinical	18
Tigecycline + Tigecycline + cIAI: Ceftriaxone with metronidazole, plus if applicable aminoglycoside + CAP: Ceftriaxone, plus if applicable oral clarithromycin	Pfizer	Phase 3	32
tigecycline	Pfizer	Phase 3	40
Zinforo (ceftaroline fosamil)	Pfizer	Pre-clinical	26
Tigecycline + Levofloxacin	Pfizer	Phase 3	40
Azithromycin	Pfizer	Phase 3	40
Telithromycin	Sanofi	Approved	43
Omadacycline + Moxifloxacin	Zai Lab	Phase 3	41
ceftobiprole medocaril + IV standard-of-care cephalosporin	Basilea Pharmaceutica	Phase 3	34
EDP-420 / Duration of Treatment - 3 days + Telithromycin / Duration of Treatment - 7 days	Enanta Pharmaceuticals	Phase 2	21