Temozolomide

Phase 2Completed

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Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Metastases of Central Nervous System

Conditions

Metastases of Central Nervous System, Melanoma, Breast Neoplasm, Carcinoma, Non-Small-Cell Lung

Trial Timeline

Dec 1, 2000 → Oct 20, 2006

NCT ID

NCT00831545

About Temozolomide

Temozolomide is a phase 2 stage product being developed by Merck for Metastases of Central Nervous System. The current trial status is completed. This product is registered under clinical trial identifier NCT00831545. Target conditions include Metastases of Central Nervous System, Melanoma, Breast Neoplasm.

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (17)

NCT ID	Phase	Status	Start	Completion	Indication
NCT01127594	Phase 1	Completed	Jul 1, 2010	Jun 1, 2014	Melanoma
NCT00638963	Phase 2	Terminated	Oct 2, 2008	Jun 30, 2010	Breast Neoplasm
NCT00686725	Approved	Completed	Jun 24, 2008	Sep 28, 2011	Glioblastoma
NCT00632203	Phase 2	Terminated	Mar 4, 2008	Jan 7, 2011	Carcinoma, Non-Small-Cell Lung
NCT00723827	Pre-clinical	Completed	Mar 1, 2008	Sep 1, 2011	Glioblastoma
NCT00626990	Phase 3	Active	Dec 1, 2007	Dec 1, 2029	Brain and Central Nervous System Tumors
NCT00687323	Phase 2	Completed	Jul 30, 2007	Dec 23, 2012	Leukemia, Acute Myeloid
NCT00725010	Pre-clinical	Completed	Apr 1, 2007	Apr 1, 2009	Glioblastoma
NCT00423150	Phase 2	Terminated	Jan 26, 2007	Jun 11, 2009	Colorectal Neoplasm
NCT00424554	Phase 2	Completed	Sep 26, 2006	Feb 16, 2011	Glioma
NCT00392171	Phase 2	Completed	Jun 9, 2006	Sep 15, 2009	Glioma
NCT00704808	Pre-clinical	Completed	May 1, 2006	Dec 1, 2008	Glioblastoma
NCT00684567	Phase 2	Completed	Sep 27, 2005	Oct 31, 2007	Glioblastoma
NCT00076856	Phase 2	Completed	Mar 31, 2004	Mar 31, 2006	Carcinoma, Non-Small-Cell Lung
NCT00783393	Phase 2	Completed	May 27, 2003	Jun 17, 2005	Astrocytoma
NCT00034697	Phase 2	Terminated	Jun 28, 2001	Jan 30, 2003	Metastases, Neoplasm
NCT00831545	Phase 2	Completed	Dec 1, 2000	Oct 20, 2006	Metastases of Central Nervous System

Competing Products

20 competing products in Metastases of Central Nervous System

See all competitors

Product	Company	Stage	Hype Score
LY2780301	Eli Lilly	Phase 1	33
Abemaciclib + Endocrine therapy	Eli Lilly	Phase 1/2	41
Patritumab deruxtecan	Daiichi Sankyo	Phase 2	52
Trastuzumab deruxtecan	Daiichi Sankyo	Phase 2	52
Denosumab + Zoledronic Acid	Daiichi Sankyo	Phase 3	77
Leuprorelin Acetate	Astellas Pharma	Phase 3	77
Pembrolizumab + Lenvatinib	Eisai	Phase 2	52
ALIMTA + folic acid + multi-vitamins	Eli Lilly	Phase 1	33
Merestinib	Eli Lilly	Phase 1	33
LY2584702 + Erlotinib + Everolimus	Eli Lilly	Phase 1	33
Veliparib + Placebo	AbbVie	Phase 2	52
temozolomide	Merck	Phase 2	52
Vorinostat	Merck	Phase 1	33
Pembrolizumab	Merck	Phase 2	52
EMD 525797	Merck	Phase 1	33
cabazitaxel + lapatinib	Novartis	Phase 2	52
BKM120 + capecitabine + Trastuzumab	Novartis	Phase 2	52
Zoledronic acid	Novartis	Phase 3	77
zoledronic acid	Novartis	Phase 1	33
capecitabine + lapatinib + trastuzumab	Novartis	Phase 3	77

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