BiotechTube

Setidegrasib + Cetuximab + Leucovorin + Oxaliplatin + Fluorouracil + Irinotecan + Nanoparticle albumin-bound-paclitaxel + Gemcitabine + Docetaxel + Pembrolizumab + Cisplatin + Carboplatin + Pemetrexed + Liposomal Irinotecan

Phase 1Recruiting
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Interest: 36/100
36
Hype Score

Development Stage

✓
Pre-clinical
2
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Solid Tumor

Conditions

Solid Tumor

Trial Timeline

Jun 8, 2022 → Dec 31, 2027

NCT ID
NCT05382559

About Setidegrasib + Cetuximab + Leucovorin + Oxaliplatin + Fluorouracil + Irinotecan + Nanoparticle albumin-bound-paclitaxel + Gemcitabine + Docetaxel + Pembrolizumab + Cisplatin + Carboplatin + Pemetrexed + Liposomal Irinotecan

Setidegrasib + Cetuximab + Leucovorin + Oxaliplatin + Fluorouracil + Irinotecan + Nanoparticle albumin-bound-paclitaxel + Gemcitabine + Docetaxel + Pembrolizumab + Cisplatin + Carboplatin + Pemetrexed + Liposomal Irinotecan is a phase 1 stage product being developed by Astellas Pharma for Solid Tumor. The current trial status is recruiting. This product is registered under clinical trial identifier NCT05382559. Target conditions include Solid Tumor.

What happened to similar drugs?

5 of 13 similar drugs in Solid Tumor were approved

Approved (5) Terminated (2) Active (8)
✅DurvalumabAstraZenecaApproved
✅ARM A : IV iron + epoietin zeta + ARM B: IV iron + epoietin zeta sequence + ARM C : single epoietin zetaRocheApproved
✅denosumab + pamidronateAmgenApproved
✅Sacituzumab Govitecan-hiyGilead SciencesApproved
✅Binimetinib only treatment + Encorafenib only Treatment + Encorafenib & Binimetinib Treatment + Treatment of Encorafenib & Binimetinib & Ribociclib + Treatment of Encorafenib & Binimetinib & CetuximabPfizerApproved
🔄olanzapine plus fosaprepitant-based triple regimen + placebo plus fosaprepitant-based triple regimenSun PharmaceuticalPhase 3
🔄MEDI4736 (Durvalumab) + MEDI4736 (Durvalumab) + TremelimumabAstraZenecaPhase 3

Hype Score Breakdown

Clinical
6
Activity
15
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT05382559Phase 1Recruiting

Competing Products

20 competing products in Solid Tumor

See all competitors
ProductCompanyStageHype Score
ALG.APV-527Alligator Bioscience ABPhase 1/2
18
ATOR-1017Alligator Bioscience ABPhase 1
19
ATOR-1015Alligator Bioscience ABPhase 1
19
mRNA-4359ModernaPhase 2
0
mRNA-2752 + DurvalumabAstraZenecaPhase 1
29
mRNA-4106ModernaPhase 1
0
mRNA-4157 + Pembrolizumab + SoC TreatmentMerckPhase 1
33
mRNA-2416ModernaPhase 2
0
E7050EisaiPhase 1
29
AFM24 + Atezolizumab 840 MG in 14 ML InjectionAffimedPhase 1/2
14
EXS21546BiotrialPhase 1/2
14
SY-1365 (Part 1) + Carboplatin + Fulvestrant + SY-1365 (Cohort 2) + SY-1365 (Cohort 5) + SY-1365 (Part 2 Single Agent)Syros PharmaceuticalsPhase 1
11
BBP-398 + sotorasibBridgeBio PharmaPhase 1
18
BBP-398 (Formerly known as IACS-15509)BridgeBio PharmaPhase 1
18
SON-1010Sonnet BioTherapeuticsPhase 1
27
SON-1010Sonnet BioTherapeuticsPhase 1/2
18
RC220 + Doxorubicin (Adriamycin)Race OncologyPhase 1
30
BT1718Bicycle TherapeuticsPhase 1/2
22
NL-201 + Pembrolizumab Injection [Keytruda]NeurogenePhase 1
19
ZN-c3 + Carboplatin + Pegylated liposomal doxorubicin + Paclitaxel + Gemcitabine + BevacizumabZentalis PharmaceuticalsPhase 1
26