Sapropterin Dihydrochloride
Phase 2Completed 0 watching 0 views this week⚡ Active
49
Development Stage
✓
Pre-clinical✓
Phase 13
Phase 24
Phase 35
ApprovedIndication / Disease
Intermittent Claudication
Conditions
Intermittent Claudication
Trial Timeline
Dec 1, 2006 → Jan 1, 2009
NCT ID
NCT00403494About Sapropterin Dihydrochloride
Sapropterin Dihydrochloride is a phase 2 stage product being developed by BioMarin Pharmaceutical for Intermittent Claudication. The current trial status is completed. This product is registered under clinical trial identifier NCT00403494. Target conditions include Intermittent Claudication.
Hype Score Breakdown
Clinical
17
Activity
12
Company
7
Novelty
5
Community
5
Clinical Trials (9)
| NCT ID | Phase | Status |
|---|---|---|
| NCT00484991 | Pre-clinical | Completed |
| NCT01274026 | Pre-clinical | Completed |
| NCT01141595 | Pre-clinical | Completed |
| NCT00838435 | Phase 3 | Completed |
| NCT00445978 | Phase 2 | Completed |
| NCT00403494 | Phase 2 | Completed |
| NCT00332189 | Phase 3 | Completed |
| NCT00225615 | Phase 3 | Completed |
| NCT00104260 | Phase 2 | Completed |
Competing Products
12 competing products in Intermittent Claudication
| Product | Company | Stage | Hype Score |
|---|---|---|---|
| Fluticasone propionate (Flovent Diskus) 250 mcg + budesonide 400 mcg | AstraZeneca | Approved | 85 |
| LLG783 + Placebo | Novartis | Phase 2 | 52 |
| Azithromycin plus chloroquine + sulfadoxine-pyrimethamine | Pfizer | Phase 3 | 76 |
| ataciguat (HMR1766) + placebo + cilostazol | Sanofi | Phase 2 | 51 |
| Ad2/HIF-1α/VP16 + Ad2/HIF-1α/VP16 + Ad2/HIF-1α/VP16 | Sanofi | Phase 2 | 51 |
| SL650472, Clopidogrel | Sanofi | Phase 2 | 51 |
| Givosiran | Alnylam Pharmaceuticals | Phase 1/2 | 38 |
| Givosiran + 5-probe cocktail | Alnylam Pharmaceuticals | Phase 1 | 30 |
| givosiran (ALN-AS1) + Sterile Normal Saline (0.9% NaCl) | Alnylam Pharmaceuticals | Phase 1 | 30 |
| Tetrahydrobiopterin 10 mg/kg + Tetrahydrobiopterin 20 mg/kg + L-Ascorbate + L-Arginine | BioMarin Pharmaceutical | Phase 1 | 30 |
| Placebo + 375 mg CK-2017357 + 500 mg CK-2017357 | Cytokinetics | Phase 2 | 49 |
| Pimavanserin 34 mg + Placebo | Acadia Pharmaceuticals | Phase 2 | 47 |