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rhASM + rhASM + rhASM + rhASM + rhASM

Phase 1Terminated
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Interest: 21/100
21
Hype Score

Development Stage

✓
Pre-clinical
2
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Acid Sphingomyelinase Deficiency

Conditions

Acid Sphingomyelinase Deficiency, Niemann-Pick Disease

Trial Timeline

Dec 1, 2006 → Apr 1, 2009

NCT ID
NCT00410566

About rhASM + rhASM + rhASM + rhASM + rhASM

rhASM + rhASM + rhASM + rhASM + rhASM is a phase 1 stage product being developed by Sanofi for Acid Sphingomyelinase Deficiency. The current trial status is terminated. This product is registered under clinical trial identifier NCT00410566. Target conditions include Acid Sphingomyelinase Deficiency, Niemann-Pick Disease.

What happened to similar drugs?

4 of 12 similar drugs in Acid Sphingomyelinase Deficiency were approved

Approved (4) Terminated (3) Active (6)
✅PantoprazolePfizerApproved
✅insulin glargine+ glulisine + NPH + Regular insulinSanofiApproved
✅Clinolipid + IntralipidBaxterApproved
✅Clinolipid + IntralipidBaxterApproved
🔄Omeprazole/sodium bicarbonate + omeprazole magnesium + sodium bicarbonateBayerPhase 3
🔄Omeprazole/sodium bicarbonate + omeprazole magnesium (20 mg equivalent)BayerPhase 3
🔄Zegerid + Prilosec OTC™ TabletsBayerPhase 3

Hype Score Breakdown

Clinical
6
Activity
0
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT00410566Phase 1Terminated

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20 competing products in Acid Sphingomyelinase Deficiency

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ONO-8539Ono PharmaceuticalPhase 1
29
LJN452 + Placebo to LJN452NovartisPhase 2
35
Insulin (Aspart Insulin [Novolog], Regular Insulin)Novo NordiskPre-clinical
26
PantoprazolePfizerApproved
43
Recombinant human acid sphingomyelinaseSanofiPhase 1
29
Olipudase alfaSanofiPre-clinical
26
insulin glargine+ glulisine + NPH + Regular insulinSanofiApproved
43
AtalurenSanofiPhase 2
27
Omeprazole/sodium bicarbonate + omeprazole magnesium + sodium bicarbonateBayerPhase 3
37
Omeprazole/sodium bicarbonate + omeprazole magnesium (20 mg equivalent)BayerPhase 3
37
Zegerid + Prilosec OTC™ TabletsBayerPhase 3
37
A3384IpsenPhase 2
32