Pregabalin + Alprazolam + Placebo

Phase 2Completed

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Interest: 35/100

Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Dental Anxiety

Conditions

Dental Anxiety

Trial Timeline

Jan 1, 2006 → Oct 1, 2006

NCT ID

NCT00245609

About Pregabalin + Alprazolam + Placebo

Pregabalin + Alprazolam + Placebo is a phase 2 stage product being developed by Pfizer for Dental Anxiety. The current trial status is completed. This product is registered under clinical trial identifier NCT00245609. Target conditions include Dental Anxiety.

What happened to similar drugs?

1 of 8 similar drugs in Dental Anxiety were approved

Approved (1) Terminated (0) Active (7)

✅2 mg nicotine gum + 4 mg nicotine gumJohnson & JohnsonApproved

🔄Test naproxen sodium tablet + Commercial naproxen sodium tablet + Commercial naproxen sodium liquid gels capsule + Placebo tabletJohnson & JohnsonPhase 3

🔄Test acetaminophen + Commercial acetaminophen + Commercial ibuprofen + PlaceboJohnson & JohnsonPhase 3

🔄acetaminophen Tablet + acetaminophen Caplet + ibuprofen Liquid-filled capsule + Placebo Tablet + Placebo Caplet + Placebo Liquid-filled capsuleJohnson & JohnsonPhase 3

🔄Diclofenac potassium + Ibuprofen + Placebo to ibuprofen + Placebo to diclofenac potassiumNovartisPhase 3

🔄Naproxen sodium and caffeine (BAY2880376) + Naproxen sodium (Aleve) + Caffeine + PlaceboBayerPhase 3

🔄Comparator: etoricoxib + Comparator: ibuprofen + Comparator: acetaminophen + codeine + Comparator: placeboOrganonPhase 3

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (1)

NCT ID	Phase	Status	Start	Completion	Indication
NCT00245609	Phase 2	Completed	Jan 1, 2006	Oct 1, 2006	Dental Anxiety

Competing Products

20 competing products in Dental Anxiety

See all competitors

Product	Company	Stage	Hype Score
Test naproxen sodium tablet + Commercial naproxen sodium tablet + Commercial naproxen sodium liquid gels capsule + Placebo tablet	Johnson & Johnson	Phase 3	40
Sodium Fluoride Dentifrice	Johnson & Johnson	Pre-clinical	26
Test acetaminophen + Commercial acetaminophen + Commercial ibuprofen + Placebo	Johnson & Johnson	Phase 3	40
Acetaminophen (ACE) (1000 mg) + Commercial ACE (1000 mg) + Commercial Ibuprofen (IBU) (400 mg) + Placebo + Placebo + Placebo	Johnson & Johnson	Phase 2	35
2 mg nicotine gum + 4 mg nicotine gum	Johnson & Johnson	Approved	43
Acetaminophen ER + Placebo	Johnson & Johnson	Phase 2	35
acetaminophen Tablet + acetaminophen Caplet + ibuprofen Liquid-filled capsule + Placebo Tablet + Placebo Caplet + Placebo Liquid-filled capsule	Johnson & Johnson	Phase 3	40
Diclofenac potassium + Ibuprofen + Placebo to ibuprofen + Placebo to diclofenac potassium	Novartis	Phase 3	40
Placebo; oral + Placebo; oral + ARRY-371797, p38 inhibitor; oral + ARRY-371797, p38 inhibitor; oral + Celecoxib, COX-2 inhibitor; oral + Placebo; oral + ARRY-371797, p38 inhibitor; oral	Pfizer	Phase 2	35
Prototype (AN0128 Toothpaste)	Pfizer	Phase 1	29
PF-05089771 + PF-05089771 + PF-05089771 + Ibuprofen	Pfizer	Phase 2	35
ARRY-371797, p38 inhibitor; oral + Placebo; oral + Placebo; oral + ARRY-371797, p38 inhibitor; oral	Pfizer	Phase 2	35
PF-04531083 + PF-04531083 + Ibuprofen	Pfizer	Phase 2	27
Naproxen sodium and caffeine (BAY2880376) + Naproxen sodium (Aleve) + Caffeine + Placebo	Bayer	Phase 3	37
XPF-001 + placebo	Xenon Pharmaceuticals	Phase 2	32
N1539 + placebo + N1539 + N1539 + Motrin	Alkermes	Phase 2	32
Comparator: etoricoxib + Comparator: ibuprofen + Comparator: acetaminophen + codeine + Comparator: placebo	Organon	Phase 3	34
Full Dose Strength + Quarter dose strength + Half dose strength + Acetaminophen standard dose + Ibuprofen low dose + Ibuprofen high dose + Placebo	AFT Pharmaceuticals	Phase 2	17
Maxigesic 325 + Acetaminophen + Ibuprofen + Placebo	AFT Pharmaceuticals	Phase 3	30
C16G2 Gel	Armata Pharmaceuticals	Phase 2	25