Posaconazole 12 mg/kg/day BID + Posaconazole 18 mg/kg/day BID + Posaconazole 18 mg/kg/day TID + Posaconazole 12 mg/kg/day TID

Phase 1Terminated

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Interest: 21/100

Hype Score

Development Stage

✓

Pre-clinical

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Fungal Infections

Conditions

Fungal Infections

Trial Timeline

Apr 17, 2008 → Apr 1, 2015

NCT ID

NCT01716234

About Posaconazole 12 mg/kg/day BID + Posaconazole 18 mg/kg/day BID + Posaconazole 18 mg/kg/day TID + Posaconazole 12 mg/kg/day TID

Posaconazole 12 mg/kg/day BID + Posaconazole 18 mg/kg/day BID + Posaconazole 18 mg/kg/day TID + Posaconazole 12 mg/kg/day TID is a phase 1 stage product being developed by Merck for Fungal Infections. The current trial status is terminated. This product is registered under clinical trial identifier NCT01716234. Target conditions include Fungal Infections.

What happened to similar drugs?

9 of 20 similar drugs in Fungal Infections were approved

Approved (9) Terminated (3) Active (10)

✅amphotericin B liposomal (Ambisome)Astellas PharmaApproved

✅PosaconazoleMerckApproved

✅Posaconazole + Calogen®MerckApproved

✅liposomal amphotericin B (AmBisome®)Gilead SciencesApproved

✅voriconazolePfizerApproved

✅Prospective TDM ArmPfizerApproved

✅voriconazolePfizerApproved

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (1)

NCT ID	Phase	Status	Start	Completion	Indication
NCT01716234	Phase 1	Terminated	Apr 17, 2008	Apr 1, 2015	Fungal Infections

Competing Products

20 competing products in Fungal Infections

See all competitors

Product	Company	Stage	Hype Score
BSG005	Alkem Laboratories	Phase 1/2	39
Micafungin	Astellas Pharma	Phase 1	29
Micafungin	Astellas Pharma	Pre-clinical	26
amphotericin B liposomal (Ambisome)	Astellas Pharma	Approved	43
Parenteral micafungin application + Other parenteral antifungal drugs	Astellas Pharma	Pre-clinical	26
Isavuconazonium sulfate + Voriconazole + Posaconazole	Astellas Pharma	Pre-clinical	26
Micafungin	Astellas Pharma	Pre-clinical	26
Micafungin	Astellas Pharma	Pre-clinical	26
Fluconazole	Astellas Pharma	Pre-clinical	26
Micafungin	Astellas Pharma	Phase 1	29
Micafungin + Placebo	Astellas Pharma	Phase 3	32
Posaconazole + Voriconazole + Placebo	Merck	Phase 3	40
caspofungin acetate + Comparator: Micafungin sodium	Merck	Phase 3	40
caspofungin acetate	Merck	Phase 3	40
Posaconazole	Merck	Phase 1	29
Posaconazole	Merck	Approved	43
Posaconazole IV 6 mg/kg + Posaconazole PFS 6 mg/kg	Merck	Phase 2	42
Posaconazole oral suspension 40 mg/mL	Merck	Pre-clinical	26
caspofungin acetate	Merck	Phase 2	35
Posaconazole	Merck	Phase 1	29