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PF-04217329 - Lowest Dose + PF-04217329 - Low Dose + PF-04217329 - Middle Dose + PF-04217329 - High Middle Dose + PF-04217329 - High Dose + PF-4217329 - Highest Dose + PF-04217329 - Vehicle + Latanoprost Vehicle + PF-04217329 - Low Dose + Latanoprost Vehicle + PF-04217329 - Middle Dose + Latanoprost Vehicle + PF-04217329 - High Dose + Latanoprost 0.005% + PF-04217329 - Low Dose + Latanoprost 0.005% + PF-04217329 - Middle Dose + Latanoprost 0.005% + PF-04217329 - High Dose + Latanoprost 0.005% + PF-04217329 - Vehicle

Phase 2Completed
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Interest: 35/100
35
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Primary Open-Angle Glaucoma

Conditions

Primary Open-Angle Glaucoma, Ocular Hypertension

Trial Timeline

Dec 11, 2007 → Jun 26, 2009

NCT ID
NCT00572455

About PF-04217329 - Lowest Dose + PF-04217329 - Low Dose + PF-04217329 - Middle Dose + PF-04217329 - High Middle Dose + PF-04217329 - High Dose + PF-4217329 - Highest Dose + PF-04217329 - Vehicle + Latanoprost Vehicle + PF-04217329 - Low Dose + Latanoprost Vehicle + PF-04217329 - Middle Dose + Latanoprost Vehicle + PF-04217329 - High Dose + Latanoprost 0.005% + PF-04217329 - Low Dose + Latanoprost 0.005% + PF-04217329 - Middle Dose + Latanoprost 0.005% + PF-04217329 - High Dose + Latanoprost 0.005% + PF-04217329 - Vehicle

PF-04217329 - Lowest Dose + PF-04217329 - Low Dose + PF-04217329 - Middle Dose + PF-04217329 - High Middle Dose + PF-04217329 - High Dose + PF-4217329 - Highest Dose + PF-04217329 - Vehicle + Latanoprost Vehicle + PF-04217329 - Low Dose + Latanoprost Vehicle + PF-04217329 - Middle Dose + Latanoprost Vehicle + PF-04217329 - High Dose + Latanoprost 0.005% + PF-04217329 - Low Dose + Latanoprost 0.005% + PF-04217329 - Middle Dose + Latanoprost 0.005% + PF-04217329 - High Dose + Latanoprost 0.005% + PF-04217329 - Vehicle is a phase 2 stage product being developed by Pfizer for Primary Open-Angle Glaucoma. The current trial status is completed. This product is registered under clinical trial identifier NCT00572455. Target conditions include Primary Open-Angle Glaucoma, Ocular Hypertension.

What happened to similar drugs?

20 of 20 similar drugs in Primary Open-Angle Glaucoma were approved

Approved (20) Terminated (6) Active (0)
✅Latanoprost plus adjunctive glaucoma medicationSight SciencesApproved
✅Bempedoic acid 180 mg tabletDaiichi SankyoApproved
✅Duloxetine + PlaceboEli LillyApproved
✅Eszopiclone + PlaceboSumitomo PharmaApproved
✅Eszopiclone + PlaceboSumitomo PharmaApproved
✅Quetiapine extended release tablet + PlaceboAstraZenecaApproved
✅RosuvastatinAstraZenecaApproved

Hype Score Breakdown

Clinical
12
Activity
8
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT00572455Phase 2Completed

Competing Products

20 competing products in Primary Open-Angle Glaucoma

See all competitors
ProductCompanyStageHype Score
Unfractionated heparinSinopharmPre-clinical
33
azenosertibZentalis PharmaceuticalsPhase 2
32
Latanoprost plus adjunctive glaucoma medicationSight SciencesApproved
25
REN001OnKure TherapeuticsPhase 1
11
Mavodelpar + PlaceboOnKure TherapeuticsPhase 2
25
REN001OnKure TherapeuticsPhase 2/3
20
SBI-100 Ophthalmic Emulsion, 0.5% + SBI-100 Ophthalmic Emulsion, 1.0% + SBI-100 Ophthalmic Emulsion, PlaceboSkye BiosciencePhase 2
25
Rituximab + Methotrexate + Cytarabine InjectionCelltrionPhase 2
31
Rituximab, lenalidomideCelltrionPhase 2
42
ibandronic acid 0.5mg + RIS placebo + 1.0mg ibandronic acid + ibandronic acid placebo + 2.5mg RISChugai PharmaceuticalPhase 3
40
CS-3150Daiichi SankyoPre-clinical
26
Bempedoic acid + Ezetimibe + Rosuvastatin + AtorvastatinDaiichi SankyoPre-clinical
33
Bempedoic acid 180 mg tabletDaiichi SankyoApproved
43
Combination of bempedoic acid and ezetimibeDaiichi SankyoPre-clinical
33
DS-8201a + T-DM1Daiichi SankyoPhase 3
44
Bempedoic acid and/or its fixed dose combination with ezetimibeDaiichi SankyoPre-clinical
18
Roxadustat + PlaceboAstellas PharmaPhase 3
32
Enzalutamide + ExemestaneAstellas PharmaPhase 2
35
Bocidelpar + PlaceboAstellas PharmaPhase 2
27
Methotrexate + Ibrutinib + TemozolomideSun PharmaceuticalPhase 2
31