Perampanel

Pre-clinicalCompleted

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Interest: 26/100

Hype Score

Development Stage

Pre-clinical

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Epilepsy

Conditions

Epilepsy, Partial-onset Seizures

Trial Timeline

Apr 11, 2016 → Jul 3, 2017

NCT ID

NCT04230044

About Perampanel

Perampanel is a pre-clinical stage product being developed by Eisai for Epilepsy. The current trial status is completed. This product is registered under clinical trial identifier NCT04230044. Target conditions include Epilepsy, Partial-onset Seizures.

What happened to similar drugs?

20 of 20 similar drugs in Epilepsy were approved

Approved (20) Terminated (6) Active (0)

✅ZonegranEisaiApproved

✅Perampanel + PlaceboEisaiApproved

✅perampanelEisaiApproved

✅Perampanel Oral TabletEisaiApproved

✅PerampanelEisaiApproved

✅zonisamide low dose group + zonisamide high dose groupEisaiApproved

✅Zonisamide at targeted daily doses of 100-500 mg/day + Placebo administered to match targeted daily doses of 100-500 mg/dayEisaiApproved

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (20)

NCT ID	Phase	Status	Start	Completion	Indication
NCT01871233	Pre-clinical	Completed	—	—	Partial Onset Seizures
NCT02307578	Pre-clinical	Completed	—	—	Primary Generalized Tonic-Clonic or Partial Onset Seizures
NCT05533814	Approved	Completed	Oct 19, 2022	Jan 23, 2025	Epilepsy
NCT04252846	Pre-clinical	Completed	Jul 20, 2020	Jan 12, 2023	Idiopathic Generalized Epilepsy
NCT03836924	Pre-clinical	Completed	Feb 18, 2019	Mar 1, 2020	Partial Onset Seizures
NCT03424564	Phase 1	Completed	Mar 20, 2018	May 25, 2018	Healthy Subjects
NCT03288129	Approved	Completed	Aug 23, 2017	Apr 27, 2021	Partial Onset Seizures
NCT02914314	Phase 2	Completed	Feb 20, 2017	Apr 25, 2023	Epilepsy
NCT02849626	Phase 3	Completed	Nov 16, 2016	Dec 6, 2021	Partial-Onset or Primary Generalized Tonic-Clonic Seizures
NCT02726074	Approved	Completed	May 3, 2016	Apr 26, 2018	Epilepsy
NCT04230044	Pre-clinical	Completed	Apr 11, 2016	Jul 3, 2017	Epilepsy
NCT04257604	Pre-clinical	Completed	Jan 3, 2016	Apr 30, 2019	Partial Seizures
NCT02727101	Approved	Terminated	Nov 1, 2015	Jul 1, 2017	Epilepsy
NCT02427607	Phase 3	Completed	May 12, 2015	Nov 9, 2016	Epilepsy
NCT02279485	Phase 1	Completed	Sep 1, 2014	Jan 1, 2015	Healthy Subjects
NCT02033902	Pre-clinical	Completed	Jun 6, 2014	Jan 31, 2018	Epilepsy
NCT01527006	Phase 2	Completed	Jan 1, 2012	Apr 1, 2015	Central Nervous System
NCT00903786	Phase 2	Completed	Jun 17, 2009	Oct 31, 2016	Refractory Partial Seizures
NCT00735397	Phase 3	Completed	Oct 1, 2008	Sep 1, 2014	Epilepsy
NCT00505622	Phase 3	Terminated	Jul 1, 2007	Apr 1, 2008	Parkinson's Disease

Competing Products

20 competing products in Epilepsy

See all competitors

Product	Company	Stage	Hype Score
perampanel	Eisai	Phase 2	35
Lacosamide	UCB	Phase 3	40
Zonisamide + Placebo	Eisai	Phase 3	32
Zonegran	Eisai	Approved	35
perampanel + perampanel	Eisai	Phase 1	29
Perampanel + Placebo	Eisai	Approved	35
perampanel	Eisai	Approved	35
E2007 + Placebo	Eisai	Phase 2	35
Placebo + Rufinamide	Eisai	Phase 3	40
E2007 (perampanel) + Placebo	Eisai	Phase 2	35
Perampanel Oral Tablet	Eisai	Approved	43
perampanel	Eisai	Phase 3	40
Perampanel	Eisai	Pre-clinical	26
Zonisamide + Carbamazepine	Eisai	Phase 3	40
Perampanel	Eisai	Approved	43
Perampanel and Microgynon-30 + Perampanel and Microgynon-30	Eisai	Phase 1	29
Perampanel	Eisai	Phase 2	35
Zonisamide + Placebo	Eisai	Phase 3	40
zonisamide low dose group + zonisamide high dose group	Eisai	Approved	43
E2007 + E2007 + Placebo	Eisai	Phase 2	35