pemetrexed

Phase 2Completed

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Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Osteosarcoma

Conditions

Osteosarcoma, Medulloblastoma, Sarcoma, Ewing's, Neuroblastoma (Measurable Disease), Neuroblastoma (Metaiodobenzylguanidine, Positive Evaluable), Rhabdomyosarcoma, Ependymoma, Non-brainstem High-grade Glioma

Trial Timeline

Sep 1, 2007 → Feb 1, 2010

NCT ID

NCT00520936

About pemetrexed

pemetrexed is a phase 2 stage product being developed by Eli Lilly for Osteosarcoma. The current trial status is completed. This product is registered under clinical trial identifier NCT00520936. Target conditions include Osteosarcoma, Medulloblastoma, Sarcoma, Ewing's.

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (20)

NCT ID	Phase	Status	Start	Completion	Indication
NCT00035061	Phase 2	Completed	—	—	Urologic Neoplasms
NCT03955042	Phase 1	Completed	Sep 6, 2019	Jan 18, 2023	Chordoma
NCT01473563	Phase 2	Completed	Dec 1, 2011	Sep 1, 2013	Nonsquamous Non-Small Cell Neoplasm of Lung
NCT00916630	Phase 1	Completed	Jan 1, 2009	Sep 1, 2015	Central Nervous System Lymphoma
NCT00732303	Phase 2	Terminated	Jan 1, 2009	Dec 1, 2010	Non-Small Cell Lung Cancer
NCT00864513	Phase 2	Terminated	Oct 1, 2007	Jul 1, 2009	Pancreas Cancer
NCT00520936	Phase 2	Completed	Sep 1, 2007	Feb 1, 2010	Osteosarcoma
NCT00523419	Phase 2	Completed	Sep 1, 2007	Jun 1, 2010	Osteosarcoma
NCT00540241	Pre-clinical	Completed	Sep 1, 2007	Mar 1, 2010	Non Small Cell Lung Cancer
NCT00497770	Pre-clinical	Completed	Feb 1, 2007	Mar 1, 2011	Lung Neoplasms
NCT00316225	Phase 2	Completed	Dec 1, 2006	Mar 1, 2009	Non-small Cell Lung Cancer
NCT00380718	Approved	Completed	Nov 1, 2006	Nov 1, 2009	Non-small Cell Lung Cancer
NCT00377520	Phase 2	Completed	Sep 1, 2006	Sep 1, 2008	Neoplasms
NCT00190918	Phase 2	Completed	Jul 1, 2006	Jul 1, 2007	Trophoblastic Neoplasms
NCT00330915	Phase 2	Completed	Jun 1, 2006	Jun 1, 2008	Rectal Neoplasms
NCT00109096	Phase 2	Completed	Jun 1, 2005	Mar 1, 2007	Ovarian Neoplasms
NCT00106002	Phase 2	Completed	Apr 1, 2005	Dec 1, 2007	Breast Cancer
NCT00216099	Phase 2	Completed	Feb 1, 2005	Mar 1, 2009	Prostate Cancer
NCT00190983	Phase 2	Completed	Feb 1, 2005	Oct 1, 2007	Cervical Intraepithelial Neoplasia
NCT00216216	Phase 2	Terminated	Jan 1, 2005	Oct 1, 2005	Small Cell Lung Cancer

Competing Products

18 competing products in Osteosarcoma

See all competitors

Product	Company	Stage	Hype Score
Azenosertib + Gemcitabine	Zentalis Pharmaceuticals	Phase 1/2	33
Lenvatinib + Ifosfamide + Etoposide + Lenvatinib	Eisai	Phase 2	52
Pemetrexed	Eli Lilly	Phase 2	52
Camrelizumab in Combination With Neoadjuvant Chemotherapy	Jiangsu Hengrui Medicine	Phase 2	52
Apatinib	Jiangsu Hengrui Medicine	Phase 2	52
Olaparib + Ceralasertib	AstraZeneca	Phase 2	52
Saracatinib + Placebo	AstraZeneca	Phase 2	52
robatumumab	Merck	Phase 2	52
Pembrolizumab	Merck	Phase 2	52
pazopanib	Novartis	Phase 2	52
Avelumab	Pfizer	Phase 2	51
Nivolumab + Azacitidine	Bristol Myers Squibb	Phase 1	32
Nivolumab + Ipilimumab	Bristol Myers Squibb	Phase 2	51
Cisplatin liposomal	Insmed	Phase 1/2	38
Cabozantinib	Ipsen	Phase 2	49
Sm-EDTMP	Jazz Pharmaceuticals	Phase 2	49
LNTH2403 Phase 1 dose + Phase 2; LNTH2403 a single agent recommended phase 2 dose (RP2D).	Lantheus Holdings	Phase 1/2	38
REOLYSIN®	Oncolytics Biotech	Phase 2	44

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