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Pembrolizumab + Standard of Care (SOC) + Lenvatinib + Olaparib + MK-4280 + MK-4280A

Phase 3Recruiting
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Interest: 47/100
47
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
✓
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Solid Tumors

Conditions

Solid Tumors, Hematologic Malignancies

Trial Timeline

Aug 21, 2018 → Aug 4, 2043

NCT ID
NCT03486873

About Pembrolizumab + Standard of Care (SOC) + Lenvatinib + Olaparib + MK-4280 + MK-4280A

Pembrolizumab + Standard of Care (SOC) + Lenvatinib + Olaparib + MK-4280 + MK-4280A is a phase 3 stage product being developed by Merck for Solid Tumors. The current trial status is recruiting. This product is registered under clinical trial identifier NCT03486873. Target conditions include Solid Tumors, Hematologic Malignancies.

What happened to similar drugs?

5 of 12 similar drugs in Solid Tumors were approved

Approved (5) Terminated (2) Active (7)
✅DurvalumabAstraZenecaApproved
✅ARM A : IV iron + epoietin zeta + ARM B: IV iron + epoietin zeta sequence + ARM C : single epoietin zetaRocheApproved
✅denosumab + pamidronateAmgenApproved
✅Sacituzumab Govitecan-hiyGilead SciencesApproved
✅Binimetinib only treatment + Encorafenib only Treatment + Encorafenib & Binimetinib Treatment + Treatment of Encorafenib & Binimetinib & Ribociclib + Treatment of Encorafenib & Binimetinib & CetuximabPfizerApproved
🔄olanzapine plus fosaprepitant-based triple regimen + placebo plus fosaprepitant-based triple regimenSun PharmaceuticalPhase 3
🔄MEDI4736 (Durvalumab) + MEDI4736 (Durvalumab) + TremelimumabAstraZenecaPhase 3

Hype Score Breakdown

Clinical
17
Activity
15
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT03486873Phase 3Recruiting

Competing Products

20 competing products in Solid Tumors

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0
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29
mRNA-4106ModernaPhase 1
0
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33
mRNA-2416ModernaPhase 2
0
E7050EisaiPhase 1
29
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14
EXS21546BiotrialPhase 1/2
14
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11
BBP-398 + sotorasibBridgeBio PharmaPhase 1
18
BBP-398 (Formerly known as IACS-15509)BridgeBio PharmaPhase 1
18
SON-1010Sonnet BioTherapeuticsPhase 1
27
SON-1010Sonnet BioTherapeuticsPhase 1/2
18
RC220 + Doxorubicin (Adriamycin)Race OncologyPhase 1
30
BT1718Bicycle TherapeuticsPhase 1/2
22
NL-201 + Pembrolizumab Injection [Keytruda]NeurogenePhase 1
19
ZN-c3 + Carboplatin + Pegylated liposomal doxorubicin + Paclitaxel + Gemcitabine + BevacizumabZentalis PharmaceuticalsPhase 1
26