Pembrolizumab + Lenvatinib

Phase 2Completed

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Interest: 35/100

Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Renal Cell Carcinoma

Conditions

Renal Cell Carcinoma

Trial Timeline

Feb 23, 2021 → Oct 21, 2025

NCT ID

NCT04704219

About Pembrolizumab + Lenvatinib

Pembrolizumab + Lenvatinib is a phase 2 stage product being developed by Eisai for Renal Cell Carcinoma. The current trial status is completed. This product is registered under clinical trial identifier NCT04704219. Target conditions include Renal Cell Carcinoma.

What happened to similar drugs?

20 of 20 similar drugs in Renal Cell Carcinoma were approved

Approved (20) Terminated (0) Active (0)

✅tacrolimus + CellCept + steroids (methylprednisone or prednisone)Astellas PharmaApproved

✅Rituximab + Tacrolimus + Mycophenylate mofetil + Hydrocortisone + Prednisolone + PrednisoloneAstellas PharmaApproved

✅Tacrolimus, Prograf®Astellas PharmaApproved

✅Astagraf XL + Prograf + Mycophenolate mofetilAstellas PharmaApproved

✅Tacrolimus - Prograf® twice daily formulation + Tacrolimus - Advagraf® once daily formulationAstellas PharmaApproved

✅Tacrolimus + CyclosporineAstellas PharmaApproved

✅Tacrolimus sustained-release capsuleAstellas PharmaApproved

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (4)

NCT ID	Phase	Status	Start	Completion	Indication
NCT05308901	Phase 2	Active	Aug 2, 2022	Jun 1, 2027	Melanoma, Uveal
NCT05064280	Phase 2	Recruiting	Jan 20, 2022	Feb 28, 2028	Brain Metastases
NCT04704219	Phase 2	Completed	Feb 23, 2021	Oct 21, 2025	Renal Cell Carcinoma
NCT03797326	Phase 2	Completed	Feb 12, 2019	Oct 28, 2024	Advanced Solid Tumors

Competing Products

20 competing products in Renal Cell Carcinoma

See all competitors

Product	Company	Stage	Hype Score
MBX 2109 + MBX 2109 + MBX 2109 + MBX 2109	MBX Biosciences	Phase 1	23
LY3473329	Eli Lilly	Phase 1	29
Tildacerfont/Placebo	Spruce Biosciences	Phase 2	17
SPR001	Spruce Biosciences	Phase 2	25
SPR001	Spruce Biosciences	Phase 2	25
Tildacerfont/Placebo	Spruce Biosciences	Phase 2	17
Tildacerfont	Spruce Biosciences	Phase 2	17
Drotrecogin alfa activated (Xigris)	Eli Lilly	Phase 2	35
LY3819469	Eli Lilly	Phase 1	29
Atezolizumab + Cabozantinib	Chugai Pharmaceutical	Phase 3	32
DS-6000a + DS-6000a	Daiichi Sankyo	Phase 1	33
DS-1093a	Daiichi Sankyo	Phase 1	29
CS-3150	Daiichi Sankyo	Phase 3	40
AGS-16C3F	Astellas Pharma	Phase 1	29
AGS-16M8F	Astellas Pharma	Phase 1	29
CP-461	Astellas Pharma	Phase 2	35
roxadustat	Astellas Pharma	Phase 3	40
YM178	Astellas Pharma	Phase 1	29
intravenous immunoglobulins (IVIG)	Astellas Pharma	Phase 1	29
bixalomer	Astellas Pharma	Pre-clinical	26