Pegloticase + Methotrexate (MTX)
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Interest: 43/100
43
Development Stage
✓
Pre-clinical✓
Phase 1✓
Phase 2✓
Phase 35
ApprovedIndication / Disease
Uncontrolled Gout
Conditions
Uncontrolled Gout, Chronic Gout
Trial Timeline
Jan 26, 2021 → Dec 20, 2023
NCT ID
NCT04762498About Pegloticase + Methotrexate (MTX)
Pegloticase + Methotrexate (MTX) is a approved stage product being developed by Amgen for Uncontrolled Gout. The current trial status is completed. This product is registered under clinical trial identifier NCT04762498. Target conditions include Uncontrolled Gout, Chronic Gout.
What happened to similar drugs?
3 of 10 similar drugs in Uncontrolled Gout were approved
Approved (3) Terminated (0) Active (7)
Hype Score Breakdown
Clinical
20
Activity
8
Company
15
Novelty
0
Community
0
Clinical Trials (2)
| NCT ID | Phase | Status |
|---|---|---|
| NCT04772313 | Approved | Completed |
| NCT04762498 | Approved | Completed |
Competing Products
17 competing products in Uncontrolled Gout
| Product | Company | Stage | Hype Score |
|---|---|---|---|
| KHK4563 + KHK4563 + KHK4563 + Placebo | Kyowa Kirin | Phase 2 | 35 |
| HR17031 injection + insulin glargine | Jiangsu Hengrui Medicine | Phase 3 | 40 |
| Baxdrostat + Placebo | AstraZeneca | Phase 3 | 44 |
| Tralokinumab | AstraZeneca | Phase 3 | 40 |
| Baxdrostat + Placebo | AstraZeneca | Phase 3 | 40 |
| Benralizumab | AstraZeneca | Phase 3 | 40 |
| Baxdrostat + Placebo | AstraZeneca | Phase 2 | 35 |
| Experimental: Tralokinumab | AstraZeneca | Phase 3 | 40 |
| Phase IIb formulation + Putative phase III formulation + Slow dissolution variant 1 + Slow dissolution variant 2 + Test treatment E | AstraZeneca | Phase 1 | 29 |
| CIN-107 + Placebo | AstraZeneca | Phase 2 | 35 |
| Pegloticase + Methotrexate (MTX) | Amgen | Approved | 43 |
| Pegloticase | Amgen | Approved | 43 |
| Pegloticase + Methotrexate | Amgen | Phase 3 | 47 |
| Pegloticase with MTX | Amgen | Approved | 43 |
| abrocitinib | Pfizer | Pre-clinical | 30 |
| REGN5381 + Placebo | Regeneron Pharmaceuticals | Phase 2 | 27 |
| SAL0140 + SAL0140 placebo | Shenzhen Salubris Pharmaceuticals | Phase 1 | 36 |