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OP-3136 + Fulvestrant + Palazestrant

Phase 1Recruiting
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Interest: 30/100
30
Hype Score

Development Stage

✓
Pre-clinical
2
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Advanced or Metastatic ER+ HER2- Breast Cancer (mBC)

Conditions

Advanced or Metastatic ER+ HER2- Breast Cancer (mBC), Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC), Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC), Metastatic Breast Cancer, Fulvestrant, Palazestrant

Trial Timeline

Dec 16, 2024 → Aug 30, 2027

NCT ID
NCT06784193

About OP-3136 + Fulvestrant + Palazestrant

OP-3136 + Fulvestrant + Palazestrant is a phase 1 stage product being developed by Olema Pharmaceuticals for Advanced or Metastatic ER+ HER2- Breast Cancer (mBC). The current trial status is recruiting. This product is registered under clinical trial identifier NCT06784193. Target conditions include Advanced or Metastatic ER+ HER2- Breast Cancer (mBC), Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC), Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC).

What happened to similar drugs?

16 of 20 similar drugs in Advanced or Metastatic ER+ HER2- Breast Cancer (mBC) were approved

Approved (16) Terminated (1) Active (4)
✅ApatinibTabletsJiangsu Hengrui MedicineApproved
✅letrozoleJiangsu Hengrui MedicineApproved
✅Levodopa-carbidopa intestinal gel (LCIG)AbbVieApproved
✅FulvestrantAstraZenecaApproved
✅Zoladex and CasodexAstraZenecaApproved
✅GefitinibAstraZenecaApproved
✅Alpelisib + FulvestrantNovartisApproved

Hype Score Breakdown

Clinical
6
Activity
15
Company
9
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT06784193Phase 1Recruiting

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