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olaparib+cediranib combination therapy + durvalumab + olaparib combination therapy + durvalumab + chemotherapy treatment + durvalumab + tremelimumab + chemotherapy treatment + durvalumab + tremelimumab + paclitaxel treatment + durvalumab +chemotherapy treatment

Phase 2UNKNOWN
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Interest: 31/100
31
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Platinum-resistant Recurrent Ovarian Cancer

Conditions

Platinum-resistant Recurrent Ovarian Cancer

Trial Timeline

Nov 26, 2018 → Sep 1, 2022

NCT ID
NCT03699449

About olaparib+cediranib combination therapy + durvalumab + olaparib combination therapy + durvalumab + chemotherapy treatment + durvalumab + tremelimumab + chemotherapy treatment + durvalumab + tremelimumab + paclitaxel treatment + durvalumab +chemotherapy treatment

olaparib+cediranib combination therapy + durvalumab + olaparib combination therapy + durvalumab + chemotherapy treatment + durvalumab + tremelimumab + chemotherapy treatment + durvalumab + tremelimumab + paclitaxel treatment + durvalumab +chemotherapy treatment is a phase 2 stage product being developed by AstraZeneca for Platinum-resistant Recurrent Ovarian Cancer. The current trial status is unknown. This product is registered under clinical trial identifier NCT03699449. Target conditions include Platinum-resistant Recurrent Ovarian Cancer.

What happened to similar drugs?

0 of 3 similar drugs in Platinum-resistant Recurrent Ovarian Cancer were approved

Approved (0) Terminated (1) Active (2)
❌Nemvaleukin and Pembrolizumab Combination + Pembrolizumab + Nemvaleukin + Pegylated Liposomal Doxorubicin (PLD) + Paclitaxel + Topotecan + GemcitabineMerckPhase 3
🔄Rina-S + Paclitaxel + Topotecan + Pegylated liposomal doxorubicin (PLD) + GemcitabineGenmabPhase 3
🔄olvimulogene nanivacirepvec + Platinum chemotherapy: carboplatin (preferred) or cisplatin + Non-platinum chemotherapy: Physician's Choice of gemcitabine, taxane (paclitaxel, docetaxel or nab-paclitaxel) or pegylated liposomal doxorubicin + Bevacizumab (or biosimilar)GeneluxPhase 3

Hype Score Breakdown

Clinical
12
Activity
4
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT03699449Phase 2UNKNOWN

Competing Products

16 competing products in Platinum-resistant Recurrent Ovarian Cancer

See all competitors
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PRGN-3005 UltraCAR-T cells + PRGN-3005 UltraCAR-T cellsPrecigenPhase 1
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Niraparib + AnlotinibSun PharmaceuticalPhase 2
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E7050 + CetuximabEisaiPhase 1/2
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Batiraxcept + DurvalumabAstraZenecaPhase 1/2
24
Nemvaleukin and Pembrolizumab Combination + Pembrolizumab + Nemvaleukin + Pegylated Liposomal Doxorubicin (PLD) + Paclitaxel + Topotecan + GemcitabineMerckPhase 3
32
CRS-207 + Epacadostat + PembrolizumabIncytePhase 1/2
21
Rina-S + Paclitaxel + Topotecan + Pegylated liposomal doxorubicin (PLD) + GemcitabineGenmabPhase 3
41
Bevacizumab + Irinotecan SucrosofateIpsenPhase 2
32
Gemcitabine + N-803 + M-CENKImmunityBioPhase 2
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Drug Product De-TIL-0255Nurix TherapeuticsPhase 1
15
Pegylated Liposomal Doxorubicin + SL-172154 + Mirvetuximab + SL-172154Shattuck LabsPhase 1
19
CTIM-76Context TherapeuticsPhase 1
26
LorigerlimabMacroGenicsPhase 2
32
olvimulogene nanivacirepvec + Platinum chemotherapy: carboplatin (preferred) or cisplatin + Non-platinum chemotherapy: Physician's Choice of gemcitabine, taxane (paclitaxel, docetaxel or nab-paclitaxel) or pegylated liposomal doxorubicin + Bevacizumab (or biosimilar)GeneluxPhase 3
37
PHI-101 administrationiBioPhase 1
15