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mRNA-1468

Phase 2Active
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Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Herpes Zoster

Conditions

Herpes Zoster

Trial Timeline

Jan 23, 2023 → Jun 30, 2026

NCT ID
NCT05701800

About mRNA-1468

mRNA-1468 is a phase 2 stage product being developed by Moderna for Herpes Zoster. The current trial status is active. This product is registered under clinical trial identifier NCT05701800. Target conditions include Herpes Zoster.

What happened to similar drugs?

5 of 20 similar drugs in Herpes Zoster were approved

Approved (5) Terminated (1) Active (14)
🔄Zoster Vaccine, LiveMerckPhase 3
🔄V212 + PlaceboMerckPhase 3
🔄zoster vaccine live (ZOSTAVAX™) + Comparator: PlaceboMerckPhase 3
🔄ZOSTAVAXMerckPhase 3
🔄Zoster Vaccine, Live (AMP) + Zoster Vaccine, LiveMerckPhase 3
🔄V212 + Matching placeboMerckPhase 3
❌V212 Lot 1 + V212 Lot 2 + V212 Lot 3MerckPhase 3

Clinical Trials (1)

NCT IDPhaseStatus
NCT05701800Phase 2Active

Competing Products

20 competing products in Herpes Zoster

See all competitors
ProductCompanyStageHype Score
mRNA-1608ModernaPhase 2
0
ASP2151 + Valacyclovir hydrochlorideAstellas PharmaPhase 2
35
ASP2151 + PlaceboAstellas PharmaPhase 1
29
ASP2151 + valacyclovir + PlaceboAstellas PharmaPhase 2
35
Dolutegravir 50 mg tablet + Dolutegravir 50 mg oral granulesShionogiPhase 1
29
GSK1349572 + EfavirenzShionogiPhase 1
29
Zoster Vaccine, Live + Comparator: PlaceboMerckPhase 2
35
Comparator: V212 + Comparator: PlaceboMerckPhase 1
29
Zoster Vaccine, LiveMerckPhase 3
40
V212 + PlaceboMerckPhase 3
40
zoster vaccine live (ZOSTAVAX™) + Comparator: PlaceboMerckPhase 3
40
ZOSTAVAXMerckPhase 3
40
Zoster Vaccine, Live (AMP) + Zoster Vaccine, LiveMerckPhase 3
40
V212 + PlaceboMerckPhase 2
35
V212 + Matching placeboMerckPhase 3
40
V212 Lot 1 + V212 Lot 2 + V212 Lot 3MerckPhase 3
32
HSV 2 Formulation 1 + HSV 2 Formulation 2 + HSV 2 Formulation 3 + HSV 2 Formulation 4 + HSV 2 Formulation 5 + HSV 2 Formulation 6 + Sodium Chloride 0.9%MerckPhase 1
21
V212 + PlaceboMerckPhase 1
29
Zoster Vaccine, Live, (Oka-Merck), ZOSTAVAX™ + Comparator: placebo (concomitant-vaccine matched) + Pneumococcal Vaccine, Polyvalent (23-valent), PNEUMOVAX™ 23MerckPhase 3
40
ZOSTAVAX™ (Zoster Vaccine Live) Full Dose Subcutaneous + ZOSTAVAX™ (Zoster Vaccine Live) 1/3 Dose Subcutaneous + ZOSTAVAX™ (Zoster Vaccine Live) Full Dose Intradermal + ZOSTAVAX™ (Zoster Vaccine Live) Partial Doses Intradermal + Full Dose Intradermal Placebo + Intradermal PlaceboMerckPhase 1
29