Mitoxantrone hydrochloride liposome Injection-based bridging therapy+ Fludarabine-based chemotherapy +CD19 CAR-T Cells
Phase 2Active 0 watching 0 views this week⚡ Active
51
Development Stage
✓
Pre-clinical✓
Phase 13
Phase 24
Phase 35
ApprovedIndication / Disease
B-cell Acute Lymphoblastic Leukemia
Conditions
B-cell Acute Lymphoblastic Leukemia, B-cell Lymphoma Refractory
Trial Timeline
Feb 1, 2022 → Dec 30, 2025
NCT ID
NCT06220097About Mitoxantrone hydrochloride liposome Injection-based bridging therapy+ Fludarabine-based chemotherapy +CD19 CAR-T Cells
Mitoxantrone hydrochloride liposome Injection-based bridging therapy+ Fludarabine-based chemotherapy +CD19 CAR-T Cells is a phase 2 stage product being developed by CSPC Pharmaceutical Group Limited for B-cell Acute Lymphoblastic Leukemia. The current trial status is active. This product is registered under clinical trial identifier NCT06220097. Target conditions include B-cell Acute Lymphoblastic Leukemia, B-cell Lymphoma Refractory.
Hype Score Breakdown
Clinical
17
Activity
12
Company
9
Novelty
5
Community
5
Clinical Trials (1)
| NCT ID | Phase | Status |
|---|---|---|
| NCT06220097 | Phase 2 | Active |
Competing Products
20 competing products in B-cell Acute Lymphoblastic Leukemia
| Product | Company | Stage | Hype Score |
|---|---|---|---|
| CD19-CAR-T cells | Avalon GloboCare | Phase 1 | 25 |
| Sepantronium Bromide | Cothera Bioscience | Phase 2 | 44 |
| rituximab | Celltrion | Phase 1 | 33 |
| Valemetostat tosylate | Daiichi Sankyo | Phase 2 | 52 |
| ASP2802 + MA-20 | Astellas Pharma | Phase 1 | 33 |
| ONTAK (denileukin diftitox) | Eisai | Phase 2 | 52 |
| Tazemetostat | Eisai | Phase 2 | 52 |
| Tazemetostat | Eisai | Phase 1 | 33 |
| ME-401 | Kyowa Kirin | Phase 1 | 33 |
| ME-401 | Kyowa Kirin | Phase 2 | 52 |
| LOXO-338 + Pirtobrutinib | Eli Lilly | Phase 1 | 33 |
| Pirtobrutinib | Eli Lilly | Pre-clinical | 23 |
| Rituximab + Gemcitabine | Eli Lilly | Phase 2 | 52 |
| Ibrutinib | Johnson & Johnson | Approved | 85 |
| Ibrutinib 420 mg + Ibrutinib 560 mg | Johnson & Johnson | Approved | 85 |
| ACALABRUTINIB + LISOCABTAGENE MARALEUCEL + Lymphodepleting chemotherapy | Johnson & Johnson | Phase 2 | 52 |
| VELCADE + Rituximab + Cyclophosphamide + Doxorubicin + Prednisone + Vincristine | Johnson & Johnson | Phase 2 | 52 |
| Ibrutinib | Johnson & Johnson | Pre-clinical | 23 |
| SHR1459 tablet + Efavirenz tablet | Jiangsu Hengrui Medicine | Phase 1 | 33 |
| SHR1459 ;YY-20394 + SHR1459 ;YY-20394 + Gemcitabine-Oxaliplatin | Jiangsu Hengrui Medicine | Phase 2 | 52 |
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