BiotechTube

Mirvetuximab Soravtansine + Paclitaxel + Topotecan + Pegylated liposomal doxorubicin

Phase 3Completed
0 views this week 0 watching⚡ Active
Interest: 40/100
40
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
✓
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Epithelial Ovarian Cancer

Conditions

Epithelial Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer

Trial Timeline

Dec 31, 2019 → Oct 29, 2024

NCT ID
NCT04209855

About Mirvetuximab Soravtansine + Paclitaxel + Topotecan + Pegylated liposomal doxorubicin

Mirvetuximab Soravtansine + Paclitaxel + Topotecan + Pegylated liposomal doxorubicin is a phase 3 stage product being developed by AbbVie for Epithelial Ovarian Cancer. The current trial status is completed. This product is registered under clinical trial identifier NCT04209855. Target conditions include Epithelial Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer.

What happened to similar drugs?

4 of 12 similar drugs in Epithelial Ovarian Cancer were approved

Approved (4) Terminated (1) Active (8)
🔄AZD5335 + Mirvetuximab Soravtansine (MIRV) + Paclitaxel + Pegylated liposomal Doxorubicin (PLD) + TopotecanAstraZenecaPhase 3
🔄Active Comparator: Olaparib tablets + PlaceboAstraZenecaPhase 3
✅Olaparib + BevacizumabAstraZenecaApproved
🔄Comparator: Quadrivalent Human Papillomavirus (HPV) vaccine + Comparator: Menactra™ (Concomitant) + Comparator: Adacel™ (Concomitant) + Comparator: Menactra™ (Non-concomitant) + Comparator: Adacel™MerckPhase 3
🔄Comparator: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant (qHPV) Vaccine from Current Manufacturing Facility (CMF) + Comparator: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant (qHPV) Vaccine from Future Manufacturing Facility (FMF) + Comparator: REPEVAX™ (Concomitant) + Comparator: REPEVAX™ (Non-Concomitant)MerckPhase 3
🔄V501MerckPhase 3
✅intravitreal injection with ranibizumabNovartisApproved

Hype Score Breakdown

Clinical
17
Activity
8
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT04209855Phase 3Completed

Competing Products

20 competing products in Epithelial Ovarian Cancer

See all competitors
ProductCompanyStageHype Score
Doxorubicin Hydrochloride Liposome InjectionDr. Reddy's LaboratoriesPhase 1
26
LY2228820 + Carboplatin + Placebo + GemcitabineEli LillyPhase 1/2
32
gemcitabine + carboplatin + paclitaxelEli LillyPhase 2
35
PemetrexedEli LillyPhase 2
35
DE-105 ophthalmic solution + DE-105 ophthalmic solution + Placebo ophthalmic solutionSanten PharmaceuticalPhase 2
35
Carboplatin + Mirvetuximab Soravtansine + BevacizumabAbbViePhase 2
42
Mirvetuximab SoravtansineAbbViePhase 2
42
AZD5335 + Mirvetuximab Soravtansine (MIRV) + Paclitaxel + Pegylated liposomal Doxorubicin (PLD) + TopotecanAstraZenecaPhase 3
47
AvelumabAstraZenecaPhase 2
27
Active Comparator: Olaparib tablets + PlaceboAstraZenecaPhase 3
40
Olaparib + carboplatin + gemcitabine or carboplatin + paclitaxel or carboplatin + liposomal doxorubicin or liposomal doxorubicin 4-weekly or topotecan or paclitaxel weeklyAstraZenecaPhase 2
31
Olaparib + BevacizumabAstraZenecaApproved
47
Comparator: Quadrivalent Human Papillomavirus (HPV) vaccine + Comparator: Menactra™ (Concomitant) + Comparator: Adacel™ (Concomitant) + Comparator: Menactra™ (Non-concomitant) + Comparator: Adacel™MerckPhase 3
40
PembrolizumabMerckPhase 2
42
MK-1775 and carboplatinMerckPhase 2
35
GardasilMerckPhase 1
29
NG-350A plus PembrolizumabMerckPhase 1
29
Comparator: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant (qHPV) Vaccine from Current Manufacturing Facility (CMF) + Comparator: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant (qHPV) Vaccine from Future Manufacturing Facility (FMF) + Comparator: REPEVAX™ (Concomitant) + Comparator: REPEVAX™ (Non-Concomitant)MerckPhase 3
40
V501MerckPhase 3
40
9-valent HPV vaccinationMerckPhase 2
42