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Meningococcal (groups A, C, W, and Y) oligosaccharide diphtheria CRM-197 conjugate vaccine

Phase 3Completed
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77
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
✓
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Meningococcal Meningitis

Conditions

Meningococcal Meningitis

Trial Timeline

Jul 1, 2010 → Apr 1, 2013

NCT ID
NCT01148017

About Meningococcal (groups A, C, W, and Y) oligosaccharide diphtheria CRM-197 conjugate vaccine

Meningococcal (groups A, C, W, and Y) oligosaccharide diphtheria CRM-197 conjugate vaccine is a phase 3 stage product being developed by Novartis for Meningococcal Meningitis. The current trial status is completed. This product is registered under clinical trial identifier NCT01148017. Target conditions include Meningococcal Meningitis.

Hype Score Breakdown

Clinical
27
Activity
18
Company
10
Novelty
9
Community
10

Clinical Trials (2)

NCT IDPhaseStatus
NCT01823536ApprovedCompleted
NCT01148017Phase 3Completed

Competing Products

20 competing products in Meningococcal Meningitis

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ProductCompanyStageHype Score
RotaTeq® + NeisVac-C®MerckPhase 3
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Meningococcal C conjugate vaccineNovartisApproved
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Meningococcal (group B) multicomponent recombinant adsorbed vaccine. + Meningococcal (group B) multicomponent recombinant adsorbed vaccine, without Outer Membrane Vesicles (OMV)NovartisPhase 2
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Meningococcal ACWY-CRM conjugate vaccine + Meningococcal ACWY-PS polysaccharide vaccineNovartisPhase 3
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1a - rMenB+OMV NZ and routine vaccines + 1b - rMenB+OMV NZ and routine vaccines + 2a - Routine and rMenB+OMV NZ vaccines + 2b - rMenB+OMV NZ and routine vaccines + 3a - rMenB+OMV NZ and routine vaccines + 3b - 1 dose of rMenB+OMV NZ plus routine infant vaccinations + 4a- rMenB+OMV NZ and routine vaccines + 4b - rMenB+OMV NZ and routine vaccinesNovartisPhase 3
77
MenACWY-CRMNovartisPre-clinical
23
Meningococcal C conjugate vaccineNovartisApproved
85
Placebo + Combined Tetanus, Reduced Diphtheria Toxoid, Acellular Pertussis Vaccine + Quadrivalent Human Papillomavirus Vaccine + MenACWY-CRM Conjugate Vaccine + Combined Tetanus, Reduced Diphtheria Toxoid, Acellular Pertussis Vaccine + Quadrivalent Human Papillomavirus VaccineNovartisApproved
85
rMenB + rMenB+OMV NZNovartisPhase 2
52
Typhoid Vi Polysaccharide Vaccine + Yellow Fever Vaccine + Japanese Encephalitis Vaccine + Rabies Vaccine + MenACWY-CRM VaccineNovartisPhase 3
77
rMenB+OMV NZNovartisPhase 3
77
Meningococcal ACWY Conjugate Vaccine + DTaP-IPV-HBV + Hib + Rotavirus + Pneumococcal 7-valent Conjugate Vaccine + HAV + MMR-V + DTaPNovartisPhase 3
77
Meningococcal (groups A, C, W, and Y) oligosaccharide diphtheria CRM-197 conjugate combined with meningococcal (group B) multicomponent recombinant vaccine + Meningococcal (group B) multicomponent recombinant adsorbed vaccine + TdapNovartisPhase 2
52
MenACWY-CRMNovartisPhase 3
77
rMenB + rMenB+OMVNovartisPhase 2
52
MenC-CRM LIQ + MenC-CRM ROS + MenC-CRM EMVNovartisPhase 2
52
Meningococcal (groups A, C, W, Y) oligosaccharide diphtheria CRM-197 conjugate combined with meningococcal (group B) multicomponent recombinant vaccine + OMV. + Meningococcal (group B) multicomponent recombinant adsorbed vaccine plus OMV. + Meningococcal (groups A, C, W, and Y) oligosaccharide diphtheria CRM-197 conjugate vaccine. + Meningococcal (groups A, C, W, Y) oligosaccharide diphtheria CRM-197 conjugate combined with meningococcal (group B) multicomponent recombinant vaccine + qOMV.NovartisPhase 2
52
MenABCWY+OMV + MenABCWY+¼OMV + PlaceboNovartisPhase 2
52
Novartis MenACWY-CRM + Saline PlaceboNovartisPhase 3
77
rMenB+OMV NZ + PlaceboNovartisPhase 2/3
65

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