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LGX818 + MEK162 + LEE011

Phase 1/2Completed
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Interest: 32/100
32
Hype Score

Development Stage

✓
Pre-clinical
2
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Solid Tumors Harboring a BRAF V600 Mutation

Conditions

Solid Tumors Harboring a BRAF V600 Mutation

Trial Timeline

May 28, 2012 → Mar 9, 2023

NCT ID
NCT01543698

About LGX818 + MEK162 + LEE011

LGX818 + MEK162 + LEE011 is a phase 1/2 stage product being developed by Pfizer for Solid Tumors Harboring a BRAF V600 Mutation. The current trial status is completed. This product is registered under clinical trial identifier NCT01543698. Target conditions include Solid Tumors Harboring a BRAF V600 Mutation.

What happened to similar drugs?

5 of 13 similar drugs in Solid Tumors Harboring a BRAF V600 Mutation were approved

Approved (5) Terminated (2) Active (8)
✅DurvalumabAstraZenecaApproved
✅ARM A : IV iron + epoietin zeta + ARM B: IV iron + epoietin zeta sequence + ARM C : single epoietin zetaRocheApproved
✅denosumab + pamidronateAmgenApproved
✅Sacituzumab Govitecan-hiyGilead SciencesApproved
✅Binimetinib only treatment + Encorafenib only Treatment + Encorafenib & Binimetinib Treatment + Treatment of Encorafenib & Binimetinib & Ribociclib + Treatment of Encorafenib & Binimetinib & CetuximabPfizerApproved
🔄olanzapine plus fosaprepitant-based triple regimen + placebo plus fosaprepitant-based triple regimenSun PharmaceuticalPhase 3
🔄MEDI4736 (Durvalumab) + MEDI4736 (Durvalumab) + TremelimumabAstraZenecaPhase 3

Hype Score Breakdown

Clinical
9
Activity
8
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT01543698Phase 1/2Completed

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