Lenvatinib

Phase 1Completed

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Interest: 29/100

Hype Score

Development Stage

✓

Pre-clinical

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Renal Impairment

Conditions

Renal Impairment, Disease Severity

Trial Timeline

Nov 1, 2011 → Oct 1, 2012

NCT ID

NCT02199379

About Lenvatinib

Lenvatinib is a phase 1 stage product being developed by Eisai for Renal Impairment. The current trial status is completed. This product is registered under clinical trial identifier NCT02199379. Target conditions include Renal Impairment, Disease Severity.

What happened to similar drugs?

20 of 20 similar drugs in Renal Impairment were approved

Approved (20) Terminated (0) Active (0)

✅tacrolimus + CellCept + steroids (methylprednisone or prednisone)Astellas PharmaApproved

✅Rituximab + Tacrolimus + Mycophenylate mofetil + Hydrocortisone + Prednisolone + PrednisoloneAstellas PharmaApproved

✅Tacrolimus, Prograf®Astellas PharmaApproved

✅Astagraf XL + Prograf + Mycophenolate mofetilAstellas PharmaApproved

✅Tacrolimus - Prograf® twice daily formulation + Tacrolimus - Advagraf® once daily formulationAstellas PharmaApproved

✅Tacrolimus + CyclosporineAstellas PharmaApproved

✅Tacrolimus sustained-release capsuleAstellas PharmaApproved

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (20)

NCT ID	Phase	Status	Start	Completion	Indication
NCT03533361	Pre-clinical	Completed	—	—	Thyroid Cancer
NCT02211222	Pre-clinical	Completed	—	Jun 1, 2015	Differentiated Thyroid Cancer
NCT05901194	Phase 1/2	Active	Jul 10, 2024	Apr 1, 2027	Hepatocellular Carcinoma Non-resectable
NCT06138769	Phase 2	Active	Jul 20, 2023	Nov 1, 2027	Hepatocellular Carcinoma
NCT05171335	Phase 2	Recruiting	Jun 20, 2022	Dec 30, 2027	Hepatocellular Carcinoma
NCT05103904	Phase 2	Recruiting	Apr 19, 2022	Nov 4, 2026	Recurrent Hepatocellular Carcinoma
NCT04321954	Phase 2	Active	Mar 9, 2021	May 27, 2026	Differentiated Thyroid Cancer
NCT04297254	Approved	Completed	Feb 4, 2021	Jul 31, 2023	Carcinoma, Hepatocellular
NCT04447755	Phase 2	Completed	Jul 30, 2020	Feb 13, 2025	Relapsed or Refractory Solid Tumors
NCT04008082	Pre-clinical	Completed	May 14, 2019	Jan 28, 2022	Carcinoma, Hepatocellular
NCT03506048	Phase 2	Terminated	Jan 16, 2019	Jun 24, 2021	Differentiated Thyroid Gland Carcinoma
NCT03009292	Phase 1	Completed	Aug 6, 2018	Aug 27, 2021	Solid Tumor
NCT03663114	Pre-clinical	Completed	Jul 2, 2018	Feb 20, 2020	Carcinoma, Hepatocellular
NCT02846766	Phase 2	Withdrawn	Jul 1, 2018	Jun 1, 2021	Cancer
NCT03433703	Phase 2	Terminated	Apr 26, 2018	Jan 7, 2019	Carcinoma, Hepatocellular
NCT03573960	Approved	Completed	Apr 1, 2018	Sep 4, 2025	Thyroid Neoplasms
NCT03168074	Phase 2	UNKNOWN	Mar 28, 2017	Mar 28, 2021	Breast Cancer
NCT02953743	Phase 1	Completed	Sep 1, 2016	Dec 28, 2020	Unresectable Hepatocellular Carcinoma (HCC)
NCT02780310	Phase 2	Active	May 19, 2016	May 1, 2026	Adenoid Cystic Carcinoma
NCT02579616	Phase 2	Completed	Oct 23, 2015	Feb 27, 2019	Biliary Tract Cancer

Competing Products

20 competing products in Renal Impairment

See all competitors

Product	Company	Stage	Hype Score
MBX 2109 + MBX 2109 + MBX 2109 + MBX 2109	MBX Biosciences	Phase 1	23
LY3473329	Eli Lilly	Phase 1	29
Tildacerfont/Placebo	Spruce Biosciences	Phase 2	17
SPR001	Spruce Biosciences	Phase 2	25
SPR001	Spruce Biosciences	Phase 2	25
Tildacerfont/Placebo	Spruce Biosciences	Phase 2	17
Tildacerfont	Spruce Biosciences	Phase 2	17
Drotrecogin alfa activated (Xigris)	Eli Lilly	Phase 2	35
LY3819469	Eli Lilly	Phase 1	29
Atezolizumab + Cabozantinib	Chugai Pharmaceutical	Phase 3	32
DS-6000a + DS-6000a	Daiichi Sankyo	Phase 1	33
DS-1093a	Daiichi Sankyo	Phase 1	29
CS-3150	Daiichi Sankyo	Phase 3	40
AGS-16C3F	Astellas Pharma	Phase 1	29
AGS-16M8F	Astellas Pharma	Phase 1	29
CP-461	Astellas Pharma	Phase 2	35
roxadustat	Astellas Pharma	Phase 3	40
YM178	Astellas Pharma	Phase 1	29
intravenous immunoglobulins (IVIG)	Astellas Pharma	Phase 1	29
bixalomer	Astellas Pharma	Pre-clinical	26